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The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE. Esser N, et al. Among authors: kahn se. Diabetologia. 2024 Sep;67(9):1897-1911. doi: 10.1007/s00125-024-06161-0. Epub 2024 Sep 9. Diabetologia. 2024. PMID: 39245780 Free PMC article.
Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials.
Kosiborod MN, Deanfield J, Pratley R, Borlaug BA, Butler J, Davies MJ, Emerson SS, Kahn SE, Kitzman DW, Lingvay I, Mahaffey KW, Petrie MC, Plutzky J, Rasmussen S, Rönnbäck C, Shah SJ, Verma S, Weeke PE, Lincoff AM; SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM Trial Committees and Investigators. Kosiborod MN, et al. Among authors: kahn se. Lancet. 2024 Sep 7;404(10456):949-961. doi: 10.1016/S0140-6736(24)01643-X. Epub 2024 Aug 30. Lancet. 2024. PMID: 39222642 Clinical Trial.
Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity (SELECT): Outcomes by Sex.
Verma S, Colhoun HM, Dicker D, Hovingh GK, Kahn SE, Kautzky-Willer A, Lingvay I, Plutzky J, Rasmussen S, Rathor N, Hoff ST, Lincoff AM. Verma S, et al. Among authors: kahn se. J Am Coll Cardiol. 2024 Oct 22;84(17):1678-1682. doi: 10.1016/j.jacc.2024.08.022. Epub 2024 Aug 30. J Am Coll Cardiol. 2024. PMID: 39217575 Free article. No abstract available.
Effective and durable repigmentation for stable vitiligo: A randomized within-subject controlled trial assessing treatment with autologous skin cell suspension transplantation.
Hamzavi IH, Ganesan AK, Mahmoud BH, Weiss E, Ahmed AM, Robinson D, Goldman MP, Munavalli G, Kahn SA, Huang V, Waibel J, Desai A, Elbuluk N, Desai S, Pandya AG. Hamzavi IH, et al. Among authors: kahn sa. J Am Acad Dermatol. 2024 Dec;91(6):1104-1112. doi: 10.1016/j.jaad.2024.08.027. Epub 2024 Sep 7. J Am Acad Dermatol. 2024. PMID: 39182674 Free article. Clinical Trial.
Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial.
Deanfield J, Verma S, Scirica BM, Kahn SE, Emerson SS, Ryan D, Lingvay I, Colhoun HM, Plutzky J, Kosiborod MN, Hovingh GK, Hardt-Lindberg S, Frenkel O, Weeke PE, Rasmussen S, Goudev A, Lang CC, Urina-Triana M, Pietilä M, Lincoff AM; SELECT Trial Investigators. Deanfield J, et al. Among authors: kahn se. Lancet. 2024 Aug 24;404(10454):773-786. doi: 10.1016/S0140-6736(24)01498-3. Lancet. 2024. PMID: 39181597 Free article. Clinical Trial.
1,867 results