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Page 1
A Multi-Target Pharmacological Correction of a Lipoyltransferase LIPT1 Gene Mutation in Patient-Derived Cellular Models.
Gómez-Fernández D, Romero-González A, Suárez-Rivero JM, Cilleros-Holgado P, Álvarez-Córdoba M, Piñero-Pérez R, Romero-Domínguez JM, Reche-López D, López-Cabrera A, Ibáñez-Mico S, Castro de Oliveira M, Rodríguez-Sacristán A, González-Granero S, García-Verdugo JM, Sánchez-Alcázar JA. Gómez-Fernández D, et al. Among authors: reche lopez d. Antioxidants (Basel). 2024 Aug 22;13(8):1023. doi: 10.3390/antiox13081023. Antioxidants (Basel). 2024. PMID: 39199267 Free PMC article.
Polydatin and Nicotinamide Rescue the Cellular Phenotype of Mitochondrial Diseases by Mitochondrial Unfolded Protein Response (mtUPR) Activation.
Cilleros-Holgado P, Gómez-Fernández D, Piñero-Pérez R, Romero Domínguez JM, Talaverón-Rey M, Reche-López D, Suárez-Rivero JM, Álvarez-Córdoba M, Romero-González A, López-Cabrera A, Oliveira MC, Rodríguez-Sacristan A, Sánchez-Alcázar JA. Cilleros-Holgado P, et al. Among authors: reche lopez d. Biomolecules. 2024 May 18;14(5):598. doi: 10.3390/biom14050598. Biomolecules. 2024. PMID: 38786005 Free PMC article.
Mitochondrial Quality Control via Mitochondrial Unfolded Protein Response (mtUPR) in Ageing and Neurodegenerative Diseases.
Cilleros-Holgado P, Gómez-Fernández D, Piñero-Pérez R, Romero-Domínguez JM, Reche-López D, López-Cabrera A, Álvarez-Córdoba M, Munuera-Cabeza M, Talaverón-Rey M, Suárez-Carrillo A, Romero-González A, Sánchez-Alcázar JA. Cilleros-Holgado P, et al. Among authors: reche lopez d. Biomolecules. 2023 Dec 13;13(12):1789. doi: 10.3390/biom13121789. Biomolecules. 2023. PMID: 38136659 Free PMC article. Review.
Actin Polymerization Defects Induce Mitochondrial Dysfunction in Cellular Models of Nemaline Myopathies.
Piñero-Pérez R, López-Cabrera A, Álvarez-Córdoba M, Cilleros-Holgado P, Talaverón-Rey M, Suárez-Carrillo A, Munuera-Cabeza M, Gómez-Fernández D, Reche-López D, Romero-González A, Romero-Domínguez JM, de Pablos RM, Sánchez-Alcázar JA. Piñero-Pérez R, et al. Among authors: reche lopez d. Antioxidants (Basel). 2023 Nov 21;12(12):2023. doi: 10.3390/antiox12122023. Antioxidants (Basel). 2023. PMID: 38136143 Free PMC article.
Patient-Derived Cellular Models for Polytarget Precision Medicine in Pantothenate Kinase-Associated Neurodegeneration.
Álvarez-Córdoba M, Talaverón-Rey M, Povea-Cabello S, Cilleros-Holgado P, Gómez-Fernández D, Piñero-Pérez R, Reche-López D, Munuera-Cabeza M, Suárez-Carrillo A, Romero-González A, Romero-Domínguez JM, López-Cabrera A, Armengol JÁ, Sánchez-Alcázar JA. Álvarez-Córdoba M, et al. Among authors: reche lopez d. Pharmaceuticals (Basel). 2023 Sep 26;16(10):1359. doi: 10.3390/ph16101359. Pharmaceuticals (Basel). 2023. PMID: 37895830 Free PMC article. Review.
Antioxidants Prevent Iron Accumulation and Lipid Peroxidation, but Do Not Correct Autophagy Dysfunction or Mitochondrial Bioenergetics in Cellular Models of BPAN.
Suárez-Carrillo A, Álvarez-Córdoba M, Romero-González A, Talaverón-Rey M, Povea-Cabello S, Cilleros-Holgado P, Piñero-Pérez R, Reche-López D, Gómez-Fernández D, Romero-Domínguez JM, Munuera-Cabeza M, Díaz A, González-Granero S, García-Verdugo JM, Sánchez-Alcázar JA. Suárez-Carrillo A, et al. Among authors: reche lopez d. Int J Mol Sci. 2023 Sep 26;24(19):14576. doi: 10.3390/ijms241914576. Int J Mol Sci. 2023. PMID: 37834028 Free PMC article.
Alpha-lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels.
Talaverón-Rey M, Álvarez-Córdoba M, Villalón-García I, Povea-Cabello S, Suárez-Rivero JM, Gómez-Fernández D, Romero-González A, Suárez-Carrillo A, Munuera-Cabeza M, Cilleros-Holgado P, Reche-López D, Piñero-Pérez R, Sánchez-Alcázar JA. Talaverón-Rey M, et al. Among authors: reche lopez d. Orphanet J Rare Dis. 2023 Apr 12;18(1):80. doi: 10.1186/s13023-023-02687-5. Orphanet J Rare Dis. 2023. PMID: 37046296 Free PMC article.
Neurodegeneration, Mitochondria, and Antibiotics.
Suárez-Rivero JM, López-Pérez J, Muela-Zarzuela I, Pastor-Maldonado C, Cilleros-Holgado P, Gómez-Fernández D, Álvarez-Córdoba M, Munuera-Cabeza M, Talaverón-Rey M, Povea-Cabello S, Suárez-Carrillo A, Piñero-Pérez R, Reche-López D, Romero-Domínguez JM, Sánchez-Alcázar JA. Suárez-Rivero JM, et al. Among authors: reche lopez d. Metabolites. 2023 Mar 12;13(3):416. doi: 10.3390/metabo13030416. Metabolites. 2023. PMID: 36984858 Free PMC article. Review.
mtUPR Modulation as a Therapeutic Target for Primary and Secondary Mitochondrial Diseases.
Cilleros-Holgado P, Gómez-Fernández D, Piñero-Pérez R, Reche-López D, Álvarez-Córdoba M, Munuera-Cabeza M, Talaverón-Rey M, Povea-Cabello S, Suárez-Carrillo A, Romero-González A, Suárez-Rivero JM, Romero-Domínguez JM, Sánchez-Alcázar JA. Cilleros-Holgado P, et al. Among authors: reche lopez d. Int J Mol Sci. 2023 Jan 12;24(2):1482. doi: 10.3390/ijms24021482. Int J Mol Sci. 2023. PMID: 36674998 Free PMC article. Review.
15 results