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Page 1
Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy.
Lutz R, Grünschläger F, Simon M, Awwad MHS, Bauer M, Yousefian S, Beumer N, Jopp-Saile L, Sedlmeier A, Solé-Boldo L, Avanesyan B, Vonficht D, Stelmach P, Steinbuss G, Boch T, Steiger S, Baertsch MA, Prokoph N, Rippe K, Durie BGM, Wickenhauser C, Trumpp A, Müller-Tidow C, Hübschmann D, Weinhold N, Raab MS, Brors B, Goldschmidt H, Imbusch CD, Hundemer M, Haas S. Lutz R, et al. Among authors: awwad mhs. Nat Commun. 2024 Nov 29;15(1):10396. doi: 10.1038/s41467-024-54543-0. Nat Commun. 2024. PMID: 39613747 Free PMC article.
CD8+ CD28- regulatory T cells after induction therapy predict progression-free survival in myeloma patients: results from the GMMG-HD6 multicenter phase III study.
Kriegsmann K, Ton GNHQ, Awwad MHS, Benner A, Bertsch U, Besemer B, Hänel M, Fenk R, Munder M, Dürig J, Blau IW, Huhn S, Hose D, Jauch A, Mann C, Weinhold N, Scheid C, Schroers R, von Metzler I, Schieferdecker A, Thomalla J, Reimer P, Mahlberg R, Graeven U, Kremers S, Martens UM, Kunz C, Hensel M, Seidel-Glätzer A, Weisel KC, Salwender HJ, Müller-Tidow C, Raab MS, Goldschmidt H, Mai EK, Hundemer M. Kriegsmann K, et al. Among authors: awwad mhs. Leukemia. 2024 Jul;38(7):1621-1625. doi: 10.1038/s41375-024-02290-y. Epub 2024 Jun 3. Leukemia. 2024. PMID: 38830959 Free PMC article. Clinical Trial. No abstract available.
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single-cell transcriptomics.
Tirier SM, Mallm JP, Steiger S, Poos AM, Awwad MHS, Giesen N, Casiraghi N, Susak H, Bauer K, Baumann A, John L, Seckinger A, Hose D, Müller-Tidow C, Goldschmidt H, Stegle O, Hundemer M, Weinhold N, Raab MS, Rippe K. Tirier SM, et al. Among authors: awwad mhs. Nat Commun. 2021 Nov 29;12(1):6960. doi: 10.1038/s41467-021-26951-z. Nat Commun. 2021. PMID: 34845188 Free PMC article.
Selective elimination of immunosuppressive T cells in patients with multiple myeloma.
Awwad MHS, Mahmoud A, Bruns H, Echchannaoui H, Kriegsmann K, Lutz R, Raab MS, Bertsch U, Munder M, Jauch A, Weisel K, Maier B, Weinhold N, Salwender HJ, Eckstein V, Hänel M, Fenk R, Dürig J, Brors B, Benner A, Müller-Tidow C, Goldschmidt H, Hundemer M. Awwad MHS, et al. Leukemia. 2021 Sep;35(9):2602-2615. doi: 10.1038/s41375-021-01172-x. Epub 2021 Feb 17. Leukemia. 2021. PMID: 33597728 Free PMC article.
The IKZF1-IRF4/IRF5 Axis Controls Polarization of Myeloma-Associated Macrophages.
Mougiakakos D, Bach C, Böttcher M, Beier F, Röhner L, Stoll A, Rehli M, Gebhard C, Lischer C, Eberhardt M, Vera J, Büttner-Herold M, Bitterer K, Balzer H, Leffler M, Jitschin S, Hundemer M, Awwad MHS, Busch M, Stenger S, Völkl S, Schütz C, Krönke J, Mackensen A, Bruns H. Mougiakakos D, et al. Among authors: awwad mhs. Cancer Immunol Res. 2021 Mar;9(3):265-278. doi: 10.1158/2326-6066.CIR-20-0555. Epub 2021 Feb 9. Cancer Immunol Res. 2021. PMID: 33563611
Comparison of NGS and MFC Methods: Key Metrics in Multiple Myeloma MRD Assessment.
Kriegsmann K, Hundemer M, Hofmeister-Mielke N, Reichert P, Manta CP, Awwad MHS, Sauer S, Bertsch U, Besemer B, Fenk R, Hänel M, Munder M, Weisel KC, Blau IW, Neubauer A, Müller-Tidow C, Raab MS, Goldschmidt H, Huhn S, For The German-Speaking Myeloma Multicenter Group Gmmg. Kriegsmann K, et al. Among authors: awwad mhs. Cancers (Basel). 2020 Aug 18;12(8):2322. doi: 10.3390/cancers12082322. Cancers (Basel). 2020. PMID: 32824635 Free PMC article.
Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients.
Kriegsmann K, Baertsch MA, Awwad MHS, Merz M, Hose D, Seckinger A, Jauch A, Becker N, Benner A, Raab MS, Hillengass J, Bertsch U, Dürig J, Salwender HJ, Hänel M, Fenk R, Munder M, Weisel K, Müller-Tidow C, Goldschmidt H, Hundemer M. Kriegsmann K, et al. Among authors: awwad mhs. Blood Cancer J. 2019 Jan 29;9(2):13. doi: 10.1038/s41408-019-0174-z. Blood Cancer J. 2019. PMID: 30696815 Free PMC article.
The prognostic and predictive value of IKZF1 and IKZF3 expression in T-cells in patients with multiple myeloma.
Awwad MHS, Kriegsmann K, Plaumann J, Benn M, Hillengass J, Raab MS, Bertsch U, Munder M, Weisel K, Salwender HJ, Hänel M, Fenk R, Dürig J, Müller-Tidow C, Goldschmidt H, Hundemer M. Awwad MHS, et al. Oncoimmunology. 2018 Aug 1;7(10):e1486356. doi: 10.1080/2162402X.2018.1486356. eCollection 2018. Oncoimmunology. 2018. PMID: 30288348 Free PMC article.
IL-10 inducible CD8+ regulatory T-cells are enriched in patients with multiple myeloma and impact the generation of antigen-specific T-cells.
Plaumann J, Engelhardt M, Awwad MHS, Echchannaoui H, Amman E, Raab MS, Hillengass J, Halama N, Neuber B, Müller-Tidow C, Goldschmidt H, Hundemer M. Plaumann J, et al. Among authors: awwad mhs. Cancer Immunol Immunother. 2018 Nov;67(11):1695-1707. doi: 10.1007/s00262-018-2230-0. Epub 2018 Aug 20. Cancer Immunol Immunother. 2018. PMID: 30128739 Free PMC article.
12 results