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Propofol binds and inhibits skeletal muscle ryanodine receptor 1.
Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Joseph TT, et al. Among authors: haji ghassemi o. Br J Anaesth. 2024 Nov;133(5):1093-1100. doi: 10.1016/j.bja.2024.06.048. Epub 2024 Sep 19. Br J Anaesth. 2024. PMID: 39304470 Free PMC article.
Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1).
Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Joseph TT, et al. Among authors: haji ghassemi o. bioRxiv [Preprint]. 2024 Jan 12:2024.01.10.575040. doi: 10.1101/2024.01.10.575040. bioRxiv. 2024. Update in: Br J Anaesth. 2024 Nov;133(5):1093-1100. doi: 10.1016/j.bja.2024.06.048 PMID: 38260485 Free PMC article. Updated. Preprint.
Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Cholak S, Saville JW, Zhu X, Berezuk AM, Tuttle KS, Haji-Ghassemi O, Alvarado FJ, Van Petegem F, Subramaniam S. Cholak S, et al. Among authors: haji ghassemi o. Structure. 2023 Jul 6;31(7):790-800.e4. doi: 10.1016/j.str.2023.04.009. Epub 2023 May 15. Structure. 2023. PMID: 37192614 Free PMC article.
Structural basis for diamide modulation of ryanodine receptor.
Ma R, Haji-Ghassemi O, Ma D, Jiang H, Lin L, Yao L, Samurkas A, Li Y, Wang Y, Cao P, Wu S, Zhang Y, Murayama T, Moussian B, Van Petegem F, Yuchi Z. Ma R, et al. Among authors: haji ghassemi o. Nat Chem Biol. 2020 Nov;16(11):1246-1254. doi: 10.1038/s41589-020-0627-5. Epub 2020 Aug 17. Nat Chem Biol. 2020. PMID: 32807966
A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Cav3.2 T-type channel activity.
Stringer RN, Jurkovicova-Tarabova B, Huang S, Haji-Ghassemi O, Idoux R, Liashenko A, Souza IA, Rzhepetskyy Y, Lacinova L, Van Petegem F, Zamponi GW, Pamphlett R, Weiss N. Stringer RN, et al. Among authors: haji ghassemi o. Mol Brain. 2020 Mar 6;13(1):33. doi: 10.1186/s13041-020-00577-6. Mol Brain. 2020. PMID: 32143681 Free PMC article.
23 results