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Page 1
Interferon epsilon is produced in the testis and protects the male reproductive tract against virus infection, inflammation and damage.
Wijayarathna R, de Geus ED, Genovese R, Gearing LJ, Wray-McCann G, Sreenivasan R, Hasan H, Fijak M, Stanton P, Fietz D, Pilatz A, Schuppe HC, Tate MD, Hertzog PJ, Hedger MP. Wijayarathna R, et al. Among authors: hertzog pj. PLoS Pathog. 2024 Dec 2;20(12):e1012702. doi: 10.1371/journal.ppat.1012702. Online ahead of print. PLoS Pathog. 2024. PMID: 39621805 Free article.
A STAT3-STING-IFN axis controls the metastatic spread of small cell lung cancer.
Guanizo AC, Luong Q, Jayasekara WSN, de Geus ED, Inampudi C, Xue VS, Chen J, de Weerd NA, Matthews AY, Gantier MP, Balic JJ, Arulananda S, Garama DJ, Hertzog PJ, Ganju V, Watkins DN, Cain JE, Gough DJ. Guanizo AC, et al. Among authors: hertzog pj. Nat Immunol. 2024 Dec;25(12):2259-2269. doi: 10.1038/s41590-024-02014-5. Epub 2024 Nov 21. Nat Immunol. 2024. PMID: 39572642
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response.
Leibel SL, McVicar RN, Murad R, Kwong EM, Clark AE, Alvarado A, Grimmig BA, Nuryyev R, Young RE, Lee JC, Peng W, Zhu YP, Griffis E, Nowell CJ, James B, Alarcon S, Malhotra A, Gearing LJ, Hertzog PJ, Galapate CM, Galenkamp KMO, Commisso C, Smith DM, Sun X, Carlin AF, Sidman RL, Croker BA, Snyder EY. Leibel SL, et al. Among authors: hertzog pj. Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2408109121. doi: 10.1073/pnas.2408109121. Epub 2024 Jul 19. Proc Natl Acad Sci U S A. 2024. PMID: 39028694 Free PMC article.
Interferon-epsilon is a novel regulator of NK cell responses in the uterus.
Mayall JR, Horvat JC, Mangan NE, Chevalier A, McCarthy H, Hampsey D, Donovan C, Brown AC, Matthews AY, de Weerd NA, de Geus ED, Starkey MR, Kim RY, Daly K, Goggins BJ, Keely S, Maltby S, Baldwin R, Foster PS, Boyle MJ, Tanwar PS, Huntington ND, Hertzog PJ, Hansbro PM. Mayall JR, et al. Among authors: hertzog pj. EMBO Mol Med. 2024 Feb;16(2):267-293. doi: 10.1038/s44321-023-00018-6. Epub 2024 Jan 23. EMBO Mol Med. 2024. PMID: 38263527 Free PMC article.
Epithelially Restricted Interferon Epsilon Protects Against Colitis.
de Geus ED, Volaric JS, Matthews AY, Mangan NE, Chang J, Ooi JD, de Weerd NA, Giles EM, Hertzog PJ. de Geus ED, et al. Among authors: hertzog pj. Cell Mol Gastroenterol Hepatol. 2024;17(2):267-278. doi: 10.1016/j.jcmgh.2023.10.006. Epub 2023 Oct 24. Cell Mol Gastroenterol Hepatol. 2024. PMID: 37879406 Free PMC article.
Interferon-ε is a tumour suppressor and restricts ovarian cancer.
Marks ZRC, Campbell NK, Mangan NE, Vandenberg CJ, Gearing LJ, Matthews AY, Gould JA, Tate MD, Wray-McCann G, Ying L, Rosli S, Brockwell N, Parker BS, Lim SS, Bilandzic M, Christie EL, Stephens AN, de Geus E, Wakefield MJ, Ho GY, McNally O; Australian Ovarian Cancer Study; McNeish IA, Bowtell DDL, de Weerd NA, Scott CL, Bourke NM, Hertzog PJ. Marks ZRC, et al. Among authors: hertzog pj. Nature. 2023 Aug;620(7976):1063-1070. doi: 10.1038/s41586-023-06421-w. Epub 2023 Aug 16. Nature. 2023. PMID: 37587335
Characterization of Monoclonal Antibodies to Measure Cell Surface Protein Levels of Human Interferon-Lambda Receptor 1.
de Weerd NA, Ogungbola O, Liu X, Matthews AY, Ismail A, Vivian JP, Lim SS, Tyrrell DL, Putcha N, Skawinski M, Dickensheets H, Lavoie TB, Donnelly RP, Hertzog PJ, Santer DM. de Weerd NA, et al. Among authors: hertzog pj. J Interferon Cytokine Res. 2023 Sep;43(9):403-413. doi: 10.1089/jir.2023.0040. Epub 2023 Jul 27. J Interferon Cytokine Res. 2023. PMID: 37499093
Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, O' Brien EC, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, O' Donnell JS, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Among authors: hertzog pj. Nat Commun. 2023 Jul 20;14(1):4374. doi: 10.1038/s41467-023-40034-1. Nat Commun. 2023. PMID: 37474527 Free PMC article. No abstract available.
203 results