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Page 1
Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
Dinkel L, Hummel S, Zenatti V, Malara M, Tillmann Y, Colombo A, Monasor LS, Suh JH, Logan T, Roth S, Paeger L, Hoffelner P, Bludau O, Schmidt A, Müller SA, Schifferer M, Nuscher B, Njavro JR, Prestel M, Bartos LM, Wind-Mark K, Slemann L, Hoermann L, Kunte ST, Gnörich J, Lindner S, Simons M, Herms J, Paquet D, Lichtenthaler SF, Bartenstein P, Franzmeier N, Liesz A, Grosche A, Bremova-Ertl T, Catarino C, Beblo S, Bergner C, Schneider SA, Strupp M, Di Paolo G, Brendel M, Tahirovic S. Dinkel L, et al. Among authors: monasor ls. Sci Transl Med. 2024 Dec 4;16(776):eadl4616. doi: 10.1126/scitranslmed.adl4616. Epub 2024 Dec 4. Sci Transl Med. 2024. PMID: 39630885
Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, Tahirovic S, Herms J, Willem M, Pettkus N, Butovsky O, Bartenstein P, Edbauer D, Rominger A, Ertürk A, Grathwohl SA, Neher JJ, Holtzman DM, Meyer-Luehmann M, Haass C. Parhizkar S, et al. Among authors: monasor ls. Nat Neurosci. 2024 Sep;27(9):1858-1859. doi: 10.1038/s41593-024-01752-x. Nat Neurosci. 2024. PMID: 39143410 No abstract available.
Towards multicenter β-amyloid PET imaging in mouse models: A triple scanner head-to-head comparison.
Gnörich J, Koehler M, Wind-Mark K, Klaus C, Zatcepin A, Palumbo G, Lalia M, Monasor LS, Beyer L, Eckenweber F, Scheifele M, Gildehaus FJ, von Ungern-Sternberg B, Barthel H, Sabri O, Bartenstein P, Herms J, Tahirovic S, Franzmeier N, Ziegler S, Brendel M. Gnörich J, et al. Among authors: monasor ls. Neuroimage. 2024 Aug 15;297:120748. doi: 10.1016/j.neuroimage.2024.120748. Epub 2024 Jul 26. Neuroimage. 2024. PMID: 39069223 Free article.
Microglia contribute to the propagation of Aβ into unaffected brain tissue.
d'Errico P, Ziegler-Waldkirch S, Aires V, Hoffmann P, Mezö C, Erny D, Monasor LS, Liebscher S, Ravi VM, Joseph K, Schnell O, Kierdorf K, Staszewski O, Tahirovic S, Prinz M, Meyer-Luehmann M. d'Errico P, et al. Among authors: monasor ls. Nat Neurosci. 2022 Jan;25(1):20-25. doi: 10.1038/s41593-021-00951-0. Epub 2021 Nov 22. Nat Neurosci. 2022. PMID: 34811521 Free PMC article.
Relationship between IGF-1 and body weight in inflammatory bowel diseases: Cellular and molecular mechanisms involved.
Guijarro LG, Cano-Martínez D, Toledo-Lobo MV, Salinas PS, Chaparro M, Gómez-Lahoz AM, Zoullas S, Rodríguez-Torres R, Román ID, Monasor LS, Ruiz-Llorente L, Del Carmen Boyano-Adánez M, Guerra I, Iborra M, Cabriada JL, Bujanda L, Taxonera C, García-Sánchez V, Marín-Jiménez I, Acosta MB, Vera I, Martín-Arranz MD, Mesonero F, Sempere L, Gomollón F, Hinojosa J, Alvarez-Mon M, Gisbert JP, Ortega MA, Hernández-Breijo B, On Behalf Of The Predicrohn Study Group From Geteccu. Guijarro LG, et al. Among authors: monasor ls. Biomed Pharmacother. 2021 Dec;144:112239. doi: 10.1016/j.biopha.2021.112239. Epub 2021 Sep 30. Biomed Pharmacother. 2021. PMID: 34601192 Free article.
Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease.
Biechele G, Monasor LS, Wind K, Blume T, Parhizkar S, Arzberger T, Sacher C, Beyer L, Eckenweber F, Gildehaus FJ, von Ungern-Sternberg B, Willem M, Bartenstein P, Cumming P, Rominger A, Herms J, Lichtenthaler SF, Haass C, Tahirovic S, Brendel M. Biechele G, et al. Among authors: monasor ls. J Nucl Med. 2022 Jan;63(1):117-124. doi: 10.2967/jnumed.120.261858. Epub 2021 May 20. J Nucl Med. 2022. PMID: 34016733 Free PMC article.
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, Tahirovic S, Herms J, Willem M, Pettkus N, Butovsky O, Bartenstein P, Edbauer D, Rominger A, Ertürk A, Grathwohl SA, Neher JJ, Holtzman DM, Meyer-Luehmann M, Haass C. Parhizkar S, et al. Among authors: monasor ls. Nat Neurosci. 2019 Feb;22(2):191-204. doi: 10.1038/s41593-018-0296-9. Epub 2019 Jan 7. Nat Neurosci. 2019. PMID: 30617257 Free PMC article.
Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.
Claes C, Van Den Daele J, Boon R, Schouteden S, Colombo A, Monasor LS, Fiers M, Ordovás L, Nami F, Bohrmann B, Tahirovic S, De Strooper B, Verfaillie CM. Claes C, et al. Among authors: monasor ls. Alzheimers Dement. 2019 Mar;15(3):453-464. doi: 10.1016/j.jalz.2018.09.006. Epub 2018 Nov 12. Alzheimers Dement. 2019. PMID: 30442540 Free article.
Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain.
Nikolakopoulou P, Chatzigeorgiou A, Kourtzelis I, Toutouna L, Masjkur J, Arps-Forker C, Poser SW, Rozman J, Rathkolb B, Aguilar-Pimentel JA; German Mouse Clinic Consortium; Wolf E, Klingenspor M, Ollert M, Schmidt-Weber C, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Tsata V, Monasor LS, Troullinaki M, Witt A, Anastasiou V, Chrousos G, Yi CX, García-Cáceres C, Tschöp MH, Bornstein SR, Androutsellis-Theotokis A. Nikolakopoulou P, et al. Among authors: monasor ls. Sci Rep. 2018 Jul 27;8(1):11335. doi: 10.1038/s41598-018-29434-2. Sci Rep. 2018. PMID: 30054579 Free PMC article.
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