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Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice.
Delfinis LJ, Khajehzadehshoushtar S, Flewwelling LD, Andrews NJ, Garibotti MC, Gandhi S, Brahmbhatt AN, Morris BA, Garlisi B, Lauks S, Aitken C, Tsitkanou S, Simpson JA, Greene NP, Cheng AJ, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: cheng aj. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.619751. doi: 10.1101/2024.10.22.619751. bioRxiv. 2024. PMID: 39484418 Free PMC article. Preprint.
Muscle weakness and mitochondrial stress occur before severe metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: cheng aj. Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. Epub 2024 Jun 24. Mol Metab. 2024. PMID: 38925248 Free PMC article.
211 results