Moran RG - Search Results

1

Phase I study of pemetrexed with sorafenib in advanced solid tumors.

Poklepovic A, Gordon S, Shafer DA, Roberts JD, Bose P, Geyer CE Jr, McGuire WP, Tombes MB, Shrader E, Strickler K, Quigley M, Wan W, Kmieciak M, Massey HD, Booth L, Moran RG, Dent P. Poklepovic A, et al. Among authors: moran rg. Oncotarget. 2016 Jul 5;7(27):42625-42638. doi: 10.18632/oncotarget.9434. Oncotarget. 2016. PMID: 27213589 Free PMC article. Clinical Trial.

2

AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells.

Agarwal S, Bell CM, Rothbart SB, Moran RG. Agarwal S, et al. Among authors: moran rg. J Biol Chem. 2015 Nov 13;290(46):27473-86. doi: 10.1074/jbc.M115.665133. Epub 2015 Sep 21. J Biol Chem. 2015. PMID: 26391395 Free PMC article.

3

p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb.

Agarwal S, Bell CM, Taylor SM, Moran RG. Agarwal S, et al. Among authors: moran rg. Mol Cancer Res. 2016 Jan;14(1):66-77. doi: 10.1158/1541-7786.MCR-15-0159. Epub 2015 Sep 18. Mol Cancer Res. 2016. PMID: 26385560 Free PMC article.

4

Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folates.

Lawrence SA, Titus SA, Ferguson J, Heineman AL, Taylor SM, Moran RG. Lawrence SA, et al. Among authors: moran rg. J Biol Chem. 2014 Oct 17;289(42):29386-96. doi: 10.1074/jbc.M114.593244. Epub 2014 Aug 27. J Biol Chem. 2014. PMID: 25164808 Free PMC article.

5

Phenylalanine-Based Inactivator of AKT Kinase: Design, Synthesis, and Biological Evaluation.

Nguyen T, Coover RA, Verghese J, Moran RG, Ellis KC. Nguyen T, et al. Among authors: moran rg. ACS Med Chem Lett. 2014 Mar 7;5(5):462-7. doi: 10.1021/ml500088x. eCollection 2014 May 8. ACS Med Chem Lett. 2014. PMID: 24900862 Free PMC article.

6

Humanizing mouse folate metabolism: conversion of the dual-promoter mouse folylpolyglutamate synthetase gene to the human single-promoter structure.

Yang C, Xie LY, Windle JJ, Taylor SM, Moran RG. Yang C, et al. Among authors: moran rg. FASEB J. 2014 May;28(5):1998-2008. doi: 10.1096/fj.13-243261. Epub 2014 Feb 14. FASEB J. 2014. PMID: 24532667 Free PMC article.

7

Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells.

Bareford MD, Hamed HA, Tang Y, Cruickshanks N, Burow ME, Fisher PB, Moran RG, Nephew KP, Grant S, Dent P. Bareford MD, et al. Among authors: moran rg. Autophagy. 2011 Oct;7(10):1261-2. doi: 10.4161/auto.7.10.17029. Epub 2011 Oct 1. Autophagy. 2011. PMID: 21814046 Free PMC article.

8

Tetrahydrofolate recognition by the mitochondrial folate transporter.

Lawrence SA, Hackett JC, Moran RG. Lawrence SA, et al. Among authors: moran rg. J Biol Chem. 2011 Sep 9;286(36):31480-9. doi: 10.1074/jbc.M111.272187. Epub 2011 Jul 15. J Biol Chem. 2011. PMID: 21768094 Free PMC article.

9

Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells.

Bareford MD, Park MA, Yacoub A, Hamed HA, Tang Y, Cruickshanks N, Eulitt P, Hubbard N, Tye G, Burow ME, Fisher PB, Moran RG, Nephew KP, Grant S, Dent P. Bareford MD, et al. Among authors: moran rg. Cancer Res. 2011 Jul 15;71(14):4955-67. doi: 10.1158/0008-5472.CAN-11-0898. Epub 2011 May 27. Cancer Res. 2011. PMID: 21622715 Free PMC article.

10

DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.

Shock LS, Thakkar PV, Peterson EJ, Moran RG, Taylor SM. Shock LS, et al. Among authors: moran rg. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3630-5. doi: 10.1073/pnas.1012311108. Epub 2011 Feb 14. Proc Natl Acad Sci U S A. 2011. PMID: 21321201 Free PMC article.

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