Widger WR - Search Results

1

Bicyclomycin and dihydrobicyclomycin inhibition kinetics of Escherichia coli rho-dependent transcription termination factor ATPase activity.

Park HG, Zhang X, Moon HS, Zwiefka A, Cox K, Gaskell SJ, Widger WR, Kohn H. Park HG, et al. Among authors: widger wr. Arch Biochem Biophys. 1995 Nov 10;323(2):447-54. doi: 10.1006/abbi.1995.0066. Arch Biochem Biophys. 1995. PMID: 7487110

2

The molecular basis for the mode of action of bicyclomycin.

Kohn H, Widger W. Kohn H, et al. Curr Drug Targets Infect Disord. 2005 Sep;5(3):273-95. doi: 10.2174/1568005054880136. Curr Drug Targets Infect Disord. 2005. PMID: 16181146 Review.

3

Mutations in the rho transcription termination factor that affect RNA tracking.

Xu Y, Kohn H, Widger WR. Xu Y, et al. Among authors: widger wr. J Biol Chem. 2002 Aug 16;277(33):30023-30. doi: 10.1074/jbc.M111009200. Epub 2002 May 28. J Biol Chem. 2002. PMID: 12034708 Free article.

4

The Mg2+ requirements for rho transcription termination factor: catalysis and bicyclomycin inhibition.

Weber TP, Widger WR, Kohn H. Weber TP, et al. Among authors: widger wr. Biochemistry. 2002 Oct 15;41(41):12377-83. doi: 10.1021/bi020420w. Biochemistry. 2002. PMID: 12369827

5

ATP binding to Rho transcription termination factor. Mutant F355W ATP-induced fluorescence quenching reveals dynamic ATP binding.

Xu Y, Johnson J, Kohn H, Widger WR. Xu Y, et al. Among authors: widger wr. J Biol Chem. 2003 Apr 18;278(16):13719-27. doi: 10.1074/jbc.M212979200. Epub 2003 Jan 27. J Biol Chem. 2003. PMID: 12551938 Free article.

6

Metal dependency for transcription factor rho activation.

Weber TP, Widger WR, Kohn H. Weber TP, et al. Among authors: widger wr. Biochemistry. 2003 Feb 18;42(6):1652-9. doi: 10.1021/bi020601y. Biochemistry. 2003. PMID: 12578379

7

Metal-1,4-dithio-2,3-dihydroxybutane chelates: novel inhibitors of the Rho transcription termination factor.

Weber TP, Widger WR, Kohn H. Weber TP, et al. Among authors: widger wr. Biochemistry. 2003 Aug 5;42(30):9121-6. doi: 10.1021/bi030089w. Biochemistry. 2003. PMID: 12885245

8

The antibiotic bicyclomycin affects the secondary RNA binding site of Escherichia coli transcription termination factor Rho.

Magyar A, Zhang X, Kohn H, Widger WR. Magyar A, et al. Among authors: widger wr. J Biol Chem. 1996 Oct 11;271(41):25369-74. doi: 10.1074/jbc.271.41.25369. J Biol Chem. 1996. PMID: 8810302 Free article.

9

Role of the C(6)-hydroxy group in bicyclomycin: synthesis, structure, and chemical, biochemical, and biological properties.

Santillán A Jr, Zhang X, Hardesty J, Widger WR, Kohn H. Santillán A Jr, et al. Among authors: widger wr. J Med Chem. 1998 Mar 26;41(7):1185-94. doi: 10.1021/jm9708386. J Med Chem. 1998. PMID: 9544218

10

Evidence for the location of bicyclomycin binding to the Escherichia coli transcription termination factor Rho.

Riba I, Gaskell SJ, Cho H, Widger WR, Kohn H. Riba I, et al. Among authors: widger wr. J Biol Chem. 1998 Dec 18;273(51):34033-41. doi: 10.1074/jbc.273.51.34033. J Biol Chem. 1998. PMID: 9852059 Free article.

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