Rose-John S - Search Results

1

Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.

Ehlers M, Grötzinger J, deHon FD, Müllberg J, Brakenhoff JP, Liu J, Wollmer A, Rose-John S. Ehlers M, et al. J Immunol. 1994 Aug 15;153(4):1744-53. J Immunol. 1994. PMID: 7519211

2

Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor.

Müllberg J, Schooltink H, Stoyan T, Heinrich PC, Rose-John S. Müllberg J, et al. Biochem Biophys Res Commun. 1992 Dec 15;189(2):794-800. doi: 10.1016/0006-291x(92)92272-y. Biochem Biophys Res Commun. 1992. PMID: 1335247

3

Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins.

Mackiewicz A, Schooltink H, Heinrich PC, Rose-John S. Mackiewicz A, et al. J Immunol. 1992 Sep 15;149(6):2021-7. J Immunol. 1992. PMID: 1381393

4

Up-regulation of the interleukin-6-signal transducing protein (gp130) by interleukin-6 and dexamethasone in HepG2 cells.

Schooltink H, Schmitz-Van de Leur H, Heinrich PC, Rose-John S. Schooltink H, et al. FEBS Lett. 1992 Feb 10;297(3):263-5. doi: 10.1016/0014-5793(92)80552-r. FEBS Lett. 1992. PMID: 1544406 Free article.

5

Structure-function analysis of human interleukin-6. Evidence for the involvement of the carboxy-terminus in function.

Krüttgen A, Rose-John S, Möller C, Wroblowski B, Wollmer A, Müllberg J, Hirano T, Kishimoto T, Heinrich PC. Krüttgen A, et al. FEBS Lett. 1990 Mar 26;262(2):323-6. doi: 10.1016/0014-5793(90)80219-9. FEBS Lett. 1990. PMID: 2335213 Free article.

6

Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.

de Hon FD, ten Boekel E, Herrman J, Clement C, Ehlers M, Taga T, Yasukawa K, Ohsugi Y, Kishimoto T, Rose-John S, et al. de Hon FD, et al. Cytokine. 1995 Jul;7(5):398-407. doi: 10.1006/cyto.1995.0055. Cytokine. 1995. PMID: 7578977

7

A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.

Müllberg J, Durie FH, Otten-Evans C, Alderson MR, Rose-John S, Cosman D, Black RA, Mohler KM. Müllberg J, et al. J Immunol. 1995 Dec 1;155(11):5198-205. J Immunol. 1995. PMID: 7594530

8

Leucine-58 in the putative 5th helical region of human interleukin (IL)-6 is important for activation of the IL-6 signal transducer, gp130.

de Hon FD, Klaasse Bos HK, Ebeling SB, Grötzinger J, Kurapkat G, Rose-John S, Aarden LA, Brakenhoff JP. de Hon FD, et al. FEBS Lett. 1995 Aug 7;369(2-3):187-91. doi: 10.1016/0014-5793(95)00741-q. FEBS Lett. 1995. PMID: 7649255 Free article.

9

The soluble interleukin-6 receptor.

Rose-John S, Ehlers M, Grötzinger J, Müllberg J. Rose-John S, et al. Ann N Y Acad Sci. 1995 Jul 21;762:207-20; discussion 220-1. Ann N Y Acad Sci. 1995. PMID: 7668529 No abstract available.

10

Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction.

Ehlers M, Grötzinger J, de Hon FD, Müllberg J, Brakenhoff JP, Wollmer A, Rose-John S. Ehlers M, et al. Ann N Y Acad Sci. 1995 Jul 21;762:400-2. doi: 10.1111/j.1749-6632.1995.tb32347.x. Ann N Y Acad Sci. 1995. PMID: 7668541 No abstract available.

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