Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
Reid SW, McAdam S, Smith KJ, Klenerman P, O'Callaghan CA, Harlos K, Jakobsen BK, McMichael AJ, Bell JI, Stuart DI, Jones EY.
Reid SW, et al. Among authors: klenerman p.
J Exp Med. 1996 Dec 1;184(6):2279-86. doi: 10.1084/jem.184.6.2279.
J Exp Med. 1996.
PMID: 8976183
Free PMC article.
In one example, lysis of antigen presenting cells by CTLs in response to recognition of an HLA B8-restricted HIV-1 P17 (aa 24-31) epitope can be inhibited by naturally occurring variants of this peptide, which act as TCR antagonists (Klenerman, P., S. Rowland Jones, …
In one example, lysis of antigen presenting cells by CTLs in response to recognition of an HLA B8-restricted HIV-1 P17 (aa 24-31) epitope ca …