Unadkat JD - Search Results

1

Dapsone acetylation by human liver arylamine N-acetyltransferases and interaction with antiopportunistic infection drugs.

Palamanda JR, Hickman D, Ward A, Sim E, Romkes-Sparks M, Unadkat JD. Palamanda JR, et al. Among authors: unadkat jd. Drug Metab Dispos. 1995 Apr;23(4):473-7. Drug Metab Dispos. 1995. PMID: 7600914

2

Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo.

Mitra AK, Thummel KE, Kalhorn TF, Kharasch ED, Unadkat JD, Slattery JT. Mitra AK, et al. Among authors: unadkat jd. Clin Pharmacol Ther. 1995 Nov;58(5):556-66. doi: 10.1016/0009-9236(95)90176-0. Clin Pharmacol Ther. 1995. PMID: 7586950 Clinical Trial.

3

Enzyme kinetic properties of human recombinant arylamine N-acetyltransferase 2 allotypic variants expressed in Escherichia coli.

Hickman D, Palamanda JR, Unadkat JD, Sim E. Hickman D, et al. Among authors: unadkat jd. Biochem Pharmacol. 1995 Aug 25;50(5):697-703. doi: 10.1016/0006-2952(95)00182-y. Biochem Pharmacol. 1995. PMID: 7669073

4

Disposition of drugs in cystic fibrosis. VII. Acetylation of sulfamethoxazole in blood cells: in vitro-in vivo correlation and characterization of its kinetics of acetylation in lymphocytes.

Hutabarat RM, Smith AL, Unadkat JD. Hutabarat RM, et al. Among authors: unadkat jd. Clin Pharmacol Ther. 1994 Apr;55(4):427-33. doi: 10.1038/clpt.1994.52. Clin Pharmacol Ther. 1994. PMID: 8162669

5

Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.

Hickman D, Wang JP, Wang Y, Unadkat JD. Hickman D, et al. Among authors: unadkat jd. Drug Metab Dispos. 1998 Mar;26(3):207-15. Drug Metab Dispos. 1998. PMID: 9492382

6

Expression of arylamine N-acetyltransferase in human intestine.

Hickman D, Pope J, Patil SD, Fakis G, Smelt V, Stanley LA, Payton M, Unadkat JD, Sim E. Hickman D, et al. Among authors: unadkat jd. Gut. 1998 Mar;42(3):402-9. doi: 10.1136/gut.42.3.402. Gut. 1998. PMID: 9577349 Free PMC article.

7

Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes.

Wang Y, Unadkat JD. Wang Y, et al. Among authors: unadkat jd. Biopharm Drug Dispos. 1999 Oct;20(7):341-6. doi: 10.1002/(sici)1099-081x(199910)20:7<341::aid-bdd195>3.0.co;2-f. Biopharm Drug Dispos. 1999. PMID: 10760842

8

CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone.

Winter HR, Wang Y, Unadkat JD. Winter HR, et al. Among authors: unadkat jd. Drug Metab Dispos. 2000 Aug;28(8):865-8. Drug Metab Dispos. 2000. PMID: 10901692

9

The effect of clarithromycin, fluconazole, and rifabutin on dapsone hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283).

Winter HR, Trapnell CB, Slattery JT, Jacobson M, Greenspan DL, Hooton TM, Unadkat JD. Winter HR, et al. Among authors: unadkat jd. Clin Pharmacol Ther. 2004 Dec;76(6):579-87. doi: 10.1016/j.clpt.2004.08.016. Clin Pharmacol Ther. 2004. PMID: 15592329 Clinical Trial.

10

Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N.

Vethanayagam RR, Wang H, Gupta A, Zhang Y, Lewis F, Unadkat JD, Mao Q. Vethanayagam RR, et al. Among authors: unadkat jd. Drug Metab Dispos. 2005 Jun;33(6):697-705. doi: 10.1124/dmd.105.003657. Epub 2005 Mar 2. Drug Metab Dispos. 2005. PMID: 15743976

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