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Novel glucocorticoid antedrugs possessing a 17beta-(gamma-lactone) ring.
Procopiou PA, Biggadike K, English AF, Farrell RM, Hagger GN, Hancock AP, Haase MV, Irving WR, Sareen M, Snowden MA, Solanke YE, Tralau-Stewart CJ, Walton SE, Wood JA. Procopiou PA, et al. Among authors: snowden ma. J Med Chem. 2001 Feb 15;44(4):602-12. doi: 10.1021/jm001035c. J Med Chem. 2001. PMID: 11170650
Selective plasma hydrolysis of glucocorticoid gamma-lactones and cyclic carbonates by the enzyme paraoxonase: an ideal plasma inactivation mechanism.
Biggadike K, Angell RM, Burgess CM, Farrell RM, Hancock AP, Harker AJ, Irving WR, Ioannou C, Procopiou PA, Shaw RE, Solanke YE, Singh OM, Snowden MA, Stubbs RJ, Walton S, Weston HE. Biggadike K, et al. Among authors: snowden ma. J Med Chem. 2000 Jan 13;43(1):19-21. doi: 10.1021/jm990436t. J Med Chem. 2000. PMID: 10633034 No abstract available.
31 results