Alagappan R - Search Results

1

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

Reijo R, Lee TY, Salo P, Alagappan R, Brown LG, Rosenberg M, Rozen S, Jaffe T, Straus D, Hovatta O, et al. Reijo R, et al. Among authors: alagappan r. Nat Genet. 1995 Aug;10(4):383-93. doi: 10.1038/ng0895-383. Nat Genet. 1995. PMID: 7670487

2

Severe oligozoospermia resulting from deletions of azoospermia factor gene on Y chromosome.

Reijo R, Alagappan RK, Patrizio P, Page DC. Reijo R, et al. Among authors: alagappan rk. Lancet. 1996 May 11;347(9011):1290-3. doi: 10.1016/s0140-6736(96)90938-1. Lancet. 1996. PMID: 8622504

3

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

Saxena R, Brown LG, Hawkins T, Alagappan RK, Skaletsky H, Reeve MP, Reijo R, Rozen S, Dinulos MB, Disteche CM, Page DC. Saxena R, et al. Among authors: alagappan rk. Nat Genet. 1996 Nov;14(3):292-9. doi: 10.1038/ng1196-292. Nat Genet. 1996. PMID: 8896558

4

Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.

Zinn AR, Alagappan RK, Brown LG, Wool I, Page DC. Zinn AR, et al. Among authors: alagappan rk. Mol Cell Biol. 1994 Apr;14(4):2485-92. doi: 10.1128/mcb.14.4.2485-2492.1994. Mol Cell Biol. 1994. PMID: 8139551 Free PMC article.

5

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

Saxena R, de Vries JW, Repping S, Alagappan RK, Skaletsky H, Brown LG, Ma P, Chen E, Hoovers JM, Page DC. Saxena R, et al. Among authors: alagappan rk. Genomics. 2000 Aug 1;67(3):256-67. doi: 10.1006/geno.2000.6260. Genomics. 2000. PMID: 10936047

6

Reconstructing hominid Y evolution: X-homologous block, created by X-Y transposition, was disrupted by Yp inversion through LINE-LINE recombination.

Schwartz A, Chan DC, Brown LG, Alagappan R, Pettay D, Disteche C, McGillivray B, de la Chapelle A, Page DC. Schwartz A, et al. Among authors: alagappan r. Hum Mol Genet. 1998 Jan;7(1):1-11. doi: 10.1093/hmg/7.1.1. Hum Mol Genet. 1998. PMID: 9384598

7

Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection.

Rozen S, Marszalek JD, Alagappan RK, Skaletsky H, Page DC. Rozen S, et al. Among authors: alagappan rk. Am J Hum Genet. 2009 Dec;85(6):923-8. doi: 10.1016/j.ajhg.2009.11.011. Am J Hum Genet. 2009. PMID: 20004767 Free PMC article.

8

Azoospermic men with deletion of the DAZ gene cluster are capable of completing spermatogenesis: fertilization, normal embryonic development and pregnancy occur when retrieved testicular spermatozoa are used for intracytoplasmic sperm injection.

Mulhall JP, Reijo R, Alagappan R, Brown L, Page D, Carson R, Oates RD. Mulhall JP, et al. Among authors: alagappan r. Hum Reprod. 1997 Mar;12(3):503-8. doi: 10.1093/humrep/12.3.503. Hum Reprod. 1997. PMID: 9130751

9

Y chromosome deletions in azoospermic and severely oligozoospermic men undergoing intracytoplasmic sperm injection after testicular sperm extraction.

Silber SJ, Alagappan R, Brown LG, Page DC. Silber SJ, et al. Among authors: alagappan r. Hum Reprod. 1998 Dec;13(12):3332-7. doi: 10.1093/humrep/13.12.3332. Hum Reprod. 1998. PMID: 9886509

10

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

Lengner CJ, Gimelbrant AA, Erwin JA, Cheng AW, Guenther MG, Welstead GG, Alagappan R, Frampton GM, Xu P, Muffat J, Santagata S, Powers D, Barrett CB, Young RA, Lee JT, Jaenisch R, Mitalipova M. Lengner CJ, et al. Among authors: alagappan r. Cell. 2010 May 28;141(5):872-83. doi: 10.1016/j.cell.2010.04.010. Epub 2010 May 13. Cell. 2010. PMID: 20471072 Free article.

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