Olefsky JM - Search Results

1

The insulin receptor C-terminus is involved in regulation of the receptor kinase activity.

Kaliman P, Baron V, Alengrin F, Takata Y, Webster NJ, Olefsky JM, Van Obberghen E. Kaliman P, et al. Among authors: olefsky jm. Biochemistry. 1993 Sep 21;32(37):9539-44. doi: 10.1021/bi00088a004. Biochemistry. 1993. PMID: 7690586

2

Deletion of exon 21 of the insulin receptor eliminates tyrosine kinase activity but preserves mitogenic signaling.

Rolband GC, Williams JF, Webster NJ, Hsu D, Olefsky JM. Rolband GC, et al. Among authors: olefsky jm. Biochemistry. 1993 Dec 14;32(49):13545-50. doi: 10.1021/bi00212a021. Biochemistry. 1993. PMID: 8257690

3

Deletion of the insulin receptor beta-subunit acidic domain results in enhanced metabolic signaling.

Rolband GC, Williams JF, Webster NJ, Olefsky JM. Rolband GC, et al. Among authors: olefsky jm. Endocrinology. 1993 Sep;133(3):1437-43. doi: 10.1210/endo.133.3.8396020. Endocrinology. 1993. PMID: 8396020

4

Mutation of the two carboxyl-terminal tyrosines results in an insulin receptor with normal metabolic signaling but enhanced mitogenic signaling properties.

Takata Y, Webster NJ, Olefsky JM. Takata Y, et al. Among authors: olefsky jm. J Biol Chem. 1991 May 15;266(14):9135-9. J Biol Chem. 1991. PMID: 2026614 Free article.

5

Intracellular signaling by a mutant human insulin receptor lacking the carboxyl-terminal tyrosine autophosphorylation sites.

Takata Y, Webster NJ, Olefsky JM. Takata Y, et al. Among authors: olefsky jm. J Biol Chem. 1992 May 5;267(13):9065-70. J Biol Chem. 1992. PMID: 1577744 Free article.

6

Transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain.

Sasaoka T, Takata Y, Kusari J, Anderson CM, Langlois WJ, Olefsky JM. Sasaoka T, et al. Among authors: olefsky jm. Proc Natl Acad Sci U S A. 1993 May 15;90(10):4379-83. doi: 10.1073/pnas.90.10.4379. Proc Natl Acad Sci U S A. 1993. PMID: 8506276 Free PMC article.

7

Insulin resistance and diabetes due to different mutations in the tyrosine kinase domain of both insulin receptor gene alleles.

Kusari J, Takata Y, Hatada E, Freidenberg G, Kolterman O, Olefsky JM. Kusari J, et al. Among authors: olefsky jm. J Biol Chem. 1991 Mar 15;266(8):5260-7. J Biol Chem. 1991. PMID: 2002058 Free article.

8

Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mitogen-activated protein kinase.

Pang L, Milarski KL, Ohmichi M, Takata Y, Olefsky JM, Saltiel AR. Pang L, et al. Among authors: olefsky jm. J Biol Chem. 1994 Apr 8;269(14):10604-8. J Biol Chem. 1994. PMID: 8144649 Free article.

9

Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors.

Draznin B, Chang L, Leitner JW, Takata Y, Olefsky JM. Draznin B, et al. Among authors: olefsky jm. J Biol Chem. 1993 Sep 25;268(27):19998-20001. J Biol Chem. 1993. PMID: 8376360 Free article.

10

Relative expression of insulin receptor isoforms does not differ in lean, obese, and noninsulin-dependent diabetes mellitus subjects.

Anderson CM, Henry RR, Knudson PE, Olefsky JM, Webster NJ. Anderson CM, et al. Among authors: olefsky jm. J Clin Endocrinol Metab. 1993 May;76(5):1380-2. doi: 10.1210/jcem.76.5.7684396. J Clin Endocrinol Metab. 1993. PMID: 7684396

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