Koboldt C - Search Results

1

Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase.

Gierse JK, Hauser SD, Creely DP, Koboldt C, Rangwala SH, Isakson PC, Seibert K. Gierse JK, et al. Among authors: koboldt c. Biochem J. 1995 Jan 15;305 ( Pt 2)(Pt 2):479-84. doi: 10.1042/bj3050479. Biochem J. 1995. PMID: 7832763 Free PMC article.

2

Expression and selective inhibition of constitutive and inducible forms of cyclooxygenase.

Seibert K, Masferrer J, Zhang Y, Leahy K, Hauser S, Gierse J, Koboldt C, Anderson G, Bremer M, Gregory S, et al. Seibert K, et al. Among authors: koboldt c. Adv Prostaglandin Thromboxane Leukot Res. 1995;23:125-7. Adv Prostaglandin Thromboxane Leukot Res. 1995. PMID: 7794421 No abstract available.

3

A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

Gierse JK, McDonald JJ, Hauser SD, Rangwala SH, Koboldt CM, Seibert K. Gierse JK, et al. Among authors: koboldt cm. J Biol Chem. 1996 Jun 28;271(26):15810-4. doi: 10.1074/jbc.271.26.15810. J Biol Chem. 1996. PMID: 8663121 Free article.

4

Kinetic basis for selective inhibition of cyclo-oxygenases.

Gierse JK, Koboldt CM, Walker MC, Seibert K, Isakson PC. Gierse JK, et al. Among authors: koboldt cm. Biochem J. 1999 May 1;339 ( Pt 3)(Pt 3):607-14. Biochem J. 1999. PMID: 10215599 Free PMC article.

5

A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors.

Walker MC, Kurumbail RG, Kiefer JR, Moreland KT, Koboldt CM, Isakson PC, Seibert K, Gierse JK. Walker MC, et al. Among authors: koboldt cm. Biochem J. 2001 Aug 1;357(Pt 3):709-18. doi: 10.1042/0264-6021:3570709. Biochem J. 2001. PMID: 11463341 Free PMC article.

6

Mechanism of inhibition of novel COX-2 inhibitors.

Gierse J, Kurumbail R, Walker M, Hood B, Monahan J, Pawlitz J, Stegeman R, Stevens A, Kiefer J, Koboldt C, Moreland K, Rowlinson S, Marnett L, Pierce J, Carter J, Talley J, Isakson P, Seibert K. Gierse J, et al. Among authors: koboldt c. Adv Exp Med Biol. 2002;507:365-9. doi: 10.1007/978-1-4615-0193-0_56. Adv Exp Med Biol. 2002. PMID: 12664611 No abstract available.

7

Cloning, expression, and selective inhibition of canine cyclooxygenase-1 and cyclooxygenase-2.

Gierse JK, Staten NR, Casperson GF, Koboldt CM, Trigg JS, Reitz BA, Pierce JL, Seibert K. Gierse JK, et al. Among authors: koboldt cm. Vet Ther. 2002 Fall;3(3):270-80. Vet Ther. 2002. PMID: 12447834

8

A structural feature of N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulfonamide (NS-398) that governs its selectivity and affinity for cyclooxygenase 2 (COX2).

Huff R, Collins P, Kramer S, Seibert K, Koboldt C, Gregory S, Isakson P. Huff R, et al. Among authors: koboldt c. Inflamm Res. 1995 Aug;44 Suppl 2:S145-6. doi: 10.1007/BF01778304. Inflamm Res. 1995. PMID: 8548370 No abstract available.

9

1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.

Li JJ, Anderson GD, Burton EG, Cogburn JN, Collins JT, Garland DJ, Gregory SA, Huang HC, Isakson PC, Koboldt CM, et al. Li JJ, et al. Among authors: koboldt cm. J Med Chem. 1995 Oct 27;38(22):4570-8. doi: 10.1021/jm00022a023. J Med Chem. 1995. PMID: 7473585

10

Novel terphenyls as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.

Li JJ, Norton MB, Reinhard EJ, Anderson GD, Gregory SA, Isakson PC, Koboldt CM, Masferrer JL, Perkins WE, Seibert K, Zhang Y, Zweifel BS, Reitz DB. Li JJ, et al. Among authors: koboldt cm. J Med Chem. 1996 Apr 26;39(9):1846-56. doi: 10.1021/jm950878e. J Med Chem. 1996. PMID: 8627608

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