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Evidence that formulations of the selective MAO-B inhibitor, selegiline, which bypass first-pass metabolism, also inhibit MAO-A in the human brain.
Fowler JS, Logan J, Volkow ND, Shumay E, McCall-Perez F, Jayne M, Wang GJ, Alexoff DL, Apelskog-Torres K, Hubbard B, Carter P, King P, Fahn S, Gilmor M, Telang F, Shea C, Xu Y, Muench L. Fowler JS, et al. Among authors: alexoff dl. Neuropsychopharmacology. 2015 Feb;40(3):650-7. doi: 10.1038/npp.2014.214. Epub 2014 Sep 24. Neuropsychopharmacology. 2015. PMID: 25249059 Free PMC article. Clinical Trial.
PET imaging of monoamine oxidase B in peripheral organs in humans.
Fowler JS, Logan J, Wang GJ, Volkow ND, Zhu W, Franceschi D, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, MacGregor RR, Schlyer D, Gatley SJ, Ding YS, Alexoff D. Fowler JS, et al. Among authors: alexoff d. J Nucl Med. 2002 Oct;43(10):1331-8. J Nucl Med. 2002. PMID: 12368371 Free article.
Strategy for the formation of parametric images under conditions of low injected radioactivity applied to PET studies with the irreversible monoamine oxidase A tracers [11C]clorgyline and deuterium-substituted [11C]clorgyline.
Logan J, Fowler JS, Ding YS, Franceschi D, Wang GJ, Volkow ND, Felder C, Alexoff D. Logan J, et al. Among authors: alexoff d. J Cereb Blood Flow Metab. 2002 Nov;22(11):1367-76. doi: 10.1097/01.WCB.0000040947.67415.e1. J Cereb Blood Flow Metab. 2002. PMID: 12439294
Monoamine oxidase A imaging in peripheral organs in healthy human subjects.
Fowler JS, Logan J, Wang GJ, Franceschi D, Volkow ND, Telang F, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, King P, Schlyer D, Gatley SJ, Ding YS, Warner D, Netusil N, Carter P, Jayne M, Alexoff D, Zhu W, Vaska P. Fowler JS, et al. Among authors: alexoff d. Synapse. 2003 Sep 1;49(3):178-87. doi: 10.1002/syn.10231. Synapse. 2003. PMID: 12774302
Comparison of the binding of the irreversible monoamine oxidase tracers, [(11)C]clorgyline and [(11)C]l-deprenyl in brain and peripheral organs in humans.
Fowler JS, Logan J, Wang GJ, Volkow ND, Telang F, Ding YS, Shea C, Garza V, Xu Y, Li Z, Alexoff D, Vaska P, Ferrieri R, Schlyer D, Zhu W, John Gatley S. Fowler JS, et al. Among authors: alexoff d. Nucl Med Biol. 2004 Apr;31(3):313-9. doi: 10.1016/j.nucmedbio.2003.10.003. Nucl Med Biol. 2004. PMID: 15028243 Clinical Trial.
124 results