Doctor BP - Search Results

1

Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases.

Saxena A, Qian N, Kovach IM, Kozikowski AP, Pang YP, Vellom DC, Radić Z, Quinn D, Taylor P, Doctor BP. Saxena A, et al. Among authors: doctor bp. Protein Sci. 1994 Oct;3(10):1770-8. doi: 10.1002/pro.5560031017. Protein Sci. 1994. PMID: 7849595 Free PMC article.

2

Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.

Saxena A, Fedorko JM, Vinayaka CR, Medhekar R, Radić Z, Taylor P, Lockridge O, Doctor BP. Saxena A, et al. Among authors: doctor bp. Eur J Biochem. 2003 Nov;270(22):4447-58. doi: 10.1046/j.1432-1033.2003.03837.x. Eur J Biochem. 2003. PMID: 14622273 Free article.

3

Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes.

Ashani Y, Radić Z, Tsigelny I, Vellom DC, Pickering NA, Quinn DM, Doctor BP, Taylor P. Ashani Y, et al. Among authors: doctor bp. J Biol Chem. 1995 Mar 17;270(11):6370-80. doi: 10.1074/jbc.270.11.6370. J Biol Chem. 1995. PMID: 7890775 Free article.

4

Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning.

Saxena A, Maxwell DM, Quinn DM, Radić Z, Taylor P, Doctor BP. Saxena A, et al. Among authors: doctor bp. Biochem Pharmacol. 1997 Jul 15;54(2):269-74. doi: 10.1016/s0006-2952(97)00180-9. Biochem Pharmacol. 1997. PMID: 9271331

5

The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism.

Saxena A, Viragh C, Frazier DS, Kovach IM, Maxwell DM, Lockridge O, Doctor BP. Saxena A, et al. Among authors: doctor bp. Biochemistry. 1998 Oct 27;37(43):15086-96. doi: 10.1021/bi980917z. Biochemistry. 1998. PMID: 9790671

6

Synthesis of more potent analogues of the acetylcholinesterase inhibitor, huperzine B.

Rajendran V, Saxena A, Doctor BP, Kozikowski AP. Rajendran V, et al. Among authors: doctor bp. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1521-3. doi: 10.1016/s0960-894x(02)00204-4. Bioorg Med Chem Lett. 2002. PMID: 12031333

7

Bioscavengers for the protection of humans against organophosphate toxicity.

Doctor BP, Saxena A. Doctor BP, et al. Chem Biol Interact. 2005 Dec 15;157-158:167-71. doi: 10.1016/j.cbi.2005.10.024. Epub 2005 Nov 15. Chem Biol Interact. 2005. PMID: 16293236

8

Comparison of methods used for the determination of cholinesterase activity in whole blood.

Naik RS, Doctor BP, Saxena A. Naik RS, et al. Among authors: doctor bp. Chem Biol Interact. 2008 Sep 25;175(1-3):298-302. doi: 10.1016/j.cbi.2008.05.002. Epub 2008 May 7. Chem Biol Interact. 2008. PMID: 18555980

9

Immunochemical characterization of anti-acetylcholinesterase inhibitory monoclonal antibodies.

Gentry MK, Saxena A, Ashani Y, Doctor BP. Gentry MK, et al. Among authors: doctor bp. Chem Biol Interact. 1993 Jun;87(1-3):227-31. doi: 10.1016/0009-2797(93)90046-2. Chem Biol Interact. 1993. PMID: 7688272

10

The role of glutamate-199 in the aging of cholinesterase.

Saxena A, Doctor BP, Maxwell DM, Lenz DE, Radic Z, Taylor P. Saxena A, et al. Among authors: doctor bp. Biochem Biophys Res Commun. 1993 Nov 30;197(1):343-9. doi: 10.1006/bbrc.1993.2481. Biochem Biophys Res Commun. 1993. PMID: 7902714

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