Kovach IM - Search Results

1

Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases.

Saxena A, Qian N, Kovach IM, Kozikowski AP, Pang YP, Vellom DC, Radić Z, Quinn D, Taylor P, Doctor BP. Saxena A, et al. Among authors: kovach im. Protein Sci. 1994 Oct;3(10):1770-8. doi: 10.1002/pro.5560031017. Protein Sci. 1994. PMID: 7849595 Free PMC article.

2

The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism.

Saxena A, Viragh C, Frazier DS, Kovach IM, Maxwell DM, Lockridge O, Doctor BP. Saxena A, et al. Among authors: kovach im. Biochemistry. 1998 Oct 27;37(43):15086-96. doi: 10.1021/bi980917z. Biochemistry. 1998. PMID: 9790671

3

Key active site residues in the inhibition of acetylcholinesterases by soman.

Qian N, Kovach IM. Qian N, et al. Among authors: kovach im. FEBS Lett. 1993 Dec 27;336(2):263-6. doi: 10.1016/0014-5793(93)80816-d. FEBS Lett. 1993. PMID: 8262242 Free article.

4

Efficient product clearance through exit channels in substrate hydrolysis by acetylcholinesterase.

Kovach IM, Qian N, Bencsura A. Kovach IM, et al. FEBS Lett. 1994 Jul 25;349(1):60-4. doi: 10.1016/0014-5793(94)00580-x. FEBS Lett. 1994. PMID: 8045303 Free article.

5

Unique push-pull mechanism of dealkylation in soman-inhibited cholinesterases.

Viragh C, Akhmetshin R, Kovach IM, Broomfield C. Viragh C, et al. Among authors: kovach im. Biochemistry. 1997 Jul 8;36(27):8243-52. doi: 10.1021/bi962764q. Biochemistry. 1997. PMID: 9204869

6

Molecular dynamics study of active-site interactions with tetracoordinate transients in acetylcholinesterase and its mutants.

Enyedy IJ, Kovach IM, Bencsura A. Enyedy IJ, et al. Among authors: kovach im. Biochem J. 2001 Feb 1;353(Pt 3):645-53. doi: 10.1042/0264-6021:3530645. Biochem J. 2001. PMID: 11171062 Free PMC article.

7

NMR evidence for a short, strong hydrogen bond at the active site of a cholinesterase.

Viragh C, Harris TK, Reddy PM, Massiah MA, Mildvan AS, Kovach IM. Viragh C, et al. Among authors: kovach im. Biochemistry. 2000 Dec 26;39(51):16200-5. doi: 10.1021/bi0022644. Biochemistry. 2000. PMID: 11123949

8

Origins and diversity of the aging reaction in phosphonate adducts of serine hydrolase enzymes: what characteristics of the active site do they probe?

Bencsura A, Enyedy I, Kovach IM. Bencsura A, et al. Among authors: kovach im. Biochemistry. 1995 Jul 18;34(28):8989-99. doi: 10.1021/bi00028a007. Biochemistry. 1995. PMID: 7619798

9

Proton bridging in the interactions of thrombin with hirudin and its mimics.

Kovach IM, Kakalis L, Jordan F, Zhang D. Kovach IM, et al. Biochemistry. 2013 Apr 9;52(14):2472-81. doi: 10.1021/bi301625a. Epub 2013 Apr 1. Biochemistry. 2013. PMID: 23517305 Free PMC article.

10

A self-consistent mechanism for dealkylation in soman-inhibited acetylcholinesterase.

Kovach IM, Akhmetshin R, Enyedy IJ, Viragh C. Kovach IM, et al. Biochem J. 1997 Jun 15;324 ( Pt 3)(Pt 3):995-6. doi: 10.1042/bj3240995. Biochem J. 1997. PMID: 9235880 Free PMC article. No abstract available.

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