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Page 1
Molecular cloning and expression of human leukotriene-C4 synthase.
Welsch DJ, Creely DP, Hauser SD, Mathis KJ, Krivi GG, Isakson PC. Welsch DJ, et al. Among authors: mathis kj. Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9745-9. doi: 10.1073/pnas.91.21.9745. Proc Natl Acad Sci U S A. 1994. PMID: 7937884 Free PMC article.
Molecular cloning and expression of human leukotriene C4 synthase.
Welsch DJ, Creely DP, Mathis KJ, Hauser SD, Isakson PC. Welsch DJ, et al. Among authors: mathis kj. Adv Prostaglandin Thromboxane Leukot Res. 1995;23:167-9. Adv Prostaglandin Thromboxane Leukot Res. 1995. PMID: 7732826 No abstract available.
Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease.
Becker DP, Barta TE, Bedell LJ, Boehm TL, Bond BR, Carroll J, Carron CP, Decrescenzo GA, Easton AM, Freskos JN, Funckes-Shippy CL, Heron M, Hockerman S, Howard CP, Kiefer JR, Li MH, Mathis KJ, McDonald JJ, Mehta PP, Munie GE, Sunyer T, Swearingen CA, Villamil CI, Welsch D, Williams JM, Yu Y, Yao J. Becker DP, et al. Among authors: mathis kj. J Med Chem. 2010 Sep 23;53(18):6653-80. doi: 10.1021/jm100669j. J Med Chem. 2010. PMID: 20726512
Secretion of active kringle-2-serine protease in Escherichia coli.
Obukowicz MG, Gustafson ME, Junger KD, Leimgruber RM, Wittwer AJ, Wun TC, Warren TG, Bishop BF, Mathis KJ, McPherson DT, et al. Obukowicz MG, et al. Among authors: mathis kj. Biochemistry. 1990 Oct 16;29(41):9737-45. doi: 10.1021/bi00493a033. Biochemistry. 1990. PMID: 2125481
MMP-13 selective α-sulfone hydroxamates: a survey of P1' heterocyclic amide isosteres.
Barta TE, Becker DP, Bedell LJ, Easton AM, Hockerman SL, Kiefer J, Munie GE, Mathis KJ, Li MH, Rico JG, Villamil CI, Williams JM. Barta TE, et al. Among authors: mathis kj. Bioorg Med Chem Lett. 2011 May 15;21(10):2820-2. doi: 10.1016/j.bmcl.2011.03.099. Epub 2011 Apr 1. Bioorg Med Chem Lett. 2011. PMID: 21507637
High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2).
Shieh HS, Mathis KJ, Williams JM, Hills RL, Wiese JF, Benson TE, Kiefer JR, Marino MH, Carroll JN, Leone JW, Malfait AM, Arner EC, Tortorella MD, Tomasselli A. Shieh HS, et al. Among authors: mathis kj. J Biol Chem. 2008 Jan 18;283(3):1501-1507. doi: 10.1074/jbc.M705879200. Epub 2007 Nov 8. J Biol Chem. 2008. PMID: 17991750 Free article.
2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor.
Trujillo JI, Kiefer JR, Huang W, Thorarensen A, Xing L, Caspers NL, Day JE, Mathis KJ, Kretzmer KK, Reitz BA, Weinberg RA, Stegeman RA, Wrightstone A, Christine L, Compton R, Li X. Trujillo JI, et al. Among authors: mathis kj. Bioorg Med Chem Lett. 2009 Feb 1;19(3):908-11. doi: 10.1016/j.bmcl.2008.11.105. Epub 2008 Dec 6. Bioorg Med Chem Lett. 2009. PMID: 19097791
Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode.
Meyers MJ, Pelc M, Kamtekar S, Day J, Poda GI, Hall MK, Michener ML, Reitz BA, Mathis KJ, Pierce BS, Parikh MD, Mischke DA, Long SA, Parlow JJ, Anderson DR, Thorarensen A. Meyers MJ, et al. Among authors: mathis kj. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1543-7. doi: 10.1016/j.bmcl.2010.01.078. Epub 2010 Jan 21. Bioorg Med Chem Lett. 2010. PMID: 20137931
28 results