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Tipranavir (PNU-140690): a potent, orally bioavailable nonpeptidic HIV protease inhibitor of the 5,6-dihydro-4-hydroxy-2-pyrone sulfonamide class.
Turner SR, Strohbach JW, Tommasi RA, Aristoff PA, Johnson PD, Skulnick HI, Dolak LA, Seest EP, Tomich PK, Bohanon MJ, Horng MM, Lynn JC, Chong KT, Hinshaw RR, Watenpaugh KD, Janakiraman MN, Thaisrivongs S. Turner SR, et al. Among authors: aristoff pa. J Med Chem. 1998 Aug 27;41(18):3467-76. doi: 10.1021/jm9802158. J Med Chem. 1998. PMID: 9719600
Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors.
Thaisrivongs S, Skulnick HI, Turner SR, Strohbach JW, Tommasi RA, Johnson PD, Aristoff PA, Judge TM, Gammill RB, Morris JK, Romines KR, Chrusciel RA, Hinshaw RR, Chong KT, Tarpley WG, Poppe SM, Slade DE, Lynn JC, Horng MM, Tomich PK, Seest EP, Dolak LA, Howe WJ, Howard GM, Watenpaugh KD, et al. Thaisrivongs S, et al. Among authors: aristoff pa. J Med Chem. 1996 Oct 25;39(22):4349-53. doi: 10.1021/jm960541s. J Med Chem. 1996. PMID: 8893827 No abstract available.
Structure-based design of nonpeptidic HIV protease inhibitors: the sulfonamide-substituted cyclooctylpyramones.
Skulnick HI, Johnson PD, Aristoff PA, Morris JK, Lovasz KD, Howe WJ, Watenpaugh KD, Janakiraman MN, Anderson DJ, Reischer RJ, Schwartz TM, Banitt LS, Tomich PK, Lynn JC, Horng MM, Chong KT, Hinshaw RR, Dolak LA, Seest EP, Schwende FJ, Rush BD, Howard GM, Toth LN, Wilkinson KR, Romines KR, et al. Skulnick HI, et al. Among authors: aristoff pa. J Med Chem. 1997 Mar 28;40(7):1149-64. doi: 10.1021/jm960441m. J Med Chem. 1997. PMID: 9089336
Sequence-selective guanine reactivity by duocarmycin A.
Mitchell MA, Weiland KL, Aristoff PA, Johnson PD, Dooley TP. Mitchell MA, et al. Among authors: aristoff pa. Chem Res Toxicol. 1993 Jul-Aug;6(4):421-4. doi: 10.1021/tx00034a005. Chem Res Toxicol. 1993. PMID: 8374036
35 results