Smad1 and smad5 act downstream of intracellular signalings of BMP-2 that inhibits myogenic differentiation and induces osteoblast differentiation in C2C12 myoblasts.
Yamamoto N, Akiyama S, Katagiri T, Namiki M, Kurokawa T, Suda T.
Yamamoto N, et al. Among authors: katagiri t.
Biochem Biophys Res Commun. 1997 Sep 18;238(2):574-80. doi: 10.1006/bbrc.1997.7325.
Biochem Biophys Res Commun. 1997.
PMID: 9299554
Bone morphogenetic protein-2 (BMP-2) inhibits terminal differentiation of C2C12 myoblasts and converts them into osteoblast lineage cells (Katagiri, T., Yamaguchi, A., Komaki, M., Abe, E., Takahashi, N., Ikeda, T., Rosen, V., Wozney, J. M., Fujisawa-Sehara, A …
Bone morphogenetic protein-2 (BMP-2) inhibits terminal differentiation of C2C12 myoblasts and converts them into osteoblast lineage cells ( …