Hopwood DA - Search Results

1

Engineered biosynthesis of novel polyketides.

McDaniel R, Ebert-Khosla S, Hopwood DA, Khosla C. McDaniel R, et al. Among authors: hopwood da. Science. 1993 Dec 3;262(5139):1546-50. doi: 10.1126/science.8248802. Science. 1993. PMID: 8248802

2

Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits.

McDaniel R, Ebert-Khosla S, Hopwood DA, Khosla C. McDaniel R, et al. Among authors: hopwood da. Nature. 1995 Jun 15;375(6532):549-54. doi: 10.1038/375549a0. Nature. 1995. PMID: 7791871

3

Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase.

McDaniel R, Ebert-Khosla S, Fu H, Hopwood DA, Khosla C. McDaniel R, et al. Among authors: hopwood da. Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11542-6. doi: 10.1073/pnas.91.24.11542. Proc Natl Acad Sci U S A. 1994. PMID: 7972098 Free PMC article.

4

Engineered biosynthesis of novel polyketides: stereochemical course of two reactions catalyzed by a polyketide synthase.

Fu H, McDaniel R, Hopwood DA, Khosla C. Fu H, et al. Among authors: hopwood da. Biochemistry. 1994 Aug 9;33(31):9321-6. doi: 10.1021/bi00197a036. Biochemistry. 1994. PMID: 8049233

5

Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor.

Fu H, Hopwood DA, Khosla C. Fu H, et al. Among authors: hopwood da. Chem Biol. 1994 Dec;1(4):205-10. doi: 10.1016/1074-5521(94)90012-4. Chem Biol. 1994. PMID: 9383392

6

Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2).

Bedford DJ, Schweizer E, Hopwood DA, Khosla C. Bedford DJ, et al. Among authors: hopwood da. J Bacteriol. 1995 Aug;177(15):4544-8. doi: 10.1128/jb.177.15.4544-4548.1995. J Bacteriol. 1995. PMID: 7635840 Free PMC article.

7

Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins.

Khosla C, McDaniel R, Ebert-Khosla S, Torres R, Sherman DH, Bibb MJ, Hopwood DA. Khosla C, et al. Among authors: hopwood da. J Bacteriol. 1993 Apr;175(8):2197-204. doi: 10.1128/jb.175.8.2197-2204.1993. J Bacteriol. 1993. PMID: 8468280 Free PMC article.

8

Engineered biosynthesis of novel polyketides: properties of the whiE aromatase/cyclase.

Alvarez MA, Fu H, Khosla C, Hopwood DA, Bailey JE. Alvarez MA, et al. Among authors: hopwood da. Nat Biotechnol. 1996 Mar;14(3):335-8. doi: 10.1038/nbt0396-335. Nat Biotechnol. 1996. PMID: 9630896

9

Directed transfer of large DNA fragments between Streptomyces species.

Hu Z, Hopwood DA, Khosla C. Hu Z, et al. Among authors: hopwood da. Appl Environ Microbiol. 2000 May;66(5):2274-7. doi: 10.1128/AEM.66.5.2274-2277.2000. Appl Environ Microbiol. 2000. PMID: 10788417 Free PMC article.

10

Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: role for the acyl carrier protein.

Khosla C, Ebert-Khosla S, Hopwood DA. Khosla C, et al. Among authors: hopwood da. Mol Microbiol. 1992 Nov;6(21):3237-49. doi: 10.1111/j.1365-2958.1992.tb01778.x. Mol Microbiol. 1992. PMID: 1453961

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