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Proof-of-concept evaluation of next-generation sequencing-based liquid biopsy for non-invasive cancer detection in cats.
Ruiz-Perez CA, Nakashe P, Marshall MA, Marass F, Tang T, McLennan LM, Kroll M, Flesner BK, Gray S, Rafalko JM, Grosu DS, Hicks SC, Tynan JA, Tsui DWY, Flory A, Kruglyak KM. Ruiz-Perez CA, et al. Among authors: mclennan lm. Front Vet Sci. 2024 Sep 13;11:1394686. doi: 10.3389/fvets.2024.1394686. eCollection 2024. Front Vet Sci. 2024. PMID: 39346958 Free PMC article.
Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial.
Pal S, Chataway J, Swingler R, Macleod MR, Carragher NO, Hardingham G, Selvaraj BT, Smith C, Wong C, Newton J, Lyle D, Stenson A, Dakin RS, Ihenacho A, Colville S, Mehta AR, Stallard N, Carpenter JR, Parker RA, Keerie C, Weir CJ, Virgo B, Morris S, Waters N, Gray B, MacDonald D, MacDonald E, Parmar MKB, Chandran S; MND SMART Investigators. Pal S, et al. Lancet Neurol. 2024 Nov;23(11):1097-1107. doi: 10.1016/S1474-4422(24)00326-0. Epub 2024 Sep 19. Lancet Neurol. 2024. PMID: 39307154 Free article. Clinical Trial.
Clinical validation of a blood-based liquid biopsy test integrating cell-free DNA quantification and next-generation sequencing for cancer screening in dogs.
Flory A, Ruiz-Perez CA, Clavere-Graciette AG, Rafalko JM, O'Kell AL, Flesner BK, McLennan LM, Hicks SC, Nakashe P, Phelps-Dunn A, DiMarzio LR, Warren CD, Cohen TA, Chibuk J, Chorny I, Grosu DS, Tsui DWY, Tynan JA, Kruglyak KM. Flory A, et al. Among authors: mclennan lm. J Am Vet Med Assoc. 2024 Feb 7;262(5):665-673. doi: 10.2460/javma.23.10.0564. Print 2024 May 1. J Am Vet Med Assoc. 2024. PMID: 38324993
Next-generation sequencing-based liquid biopsy may be used for detection of residual disease and cancer recurrence monitoring in dogs.
McCleary-Wheeler AL, Fiaux PC, Flesner BK, Ruiz-Perez CA, McLennan LM, Tynan JA, Hicks SC, Rafalko JM, Grosu DS, Chibuk J, O'Kell AL, Cohen TA, Chorny I, Tsui DWY, Kruglyak KM, Flory A. McCleary-Wheeler AL, et al. Among authors: mclennan lm. Am J Vet Res. 2023 Dec 28:1-8. doi: 10.2460/ajvr.23.07.0163. Online ahead of print. Am J Vet Res. 2023. PMID: 38150822 Free article.
40 results