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Feeding dogs a high-fat diet induces metabolic changes similar to natural aging, including dyslipidemia, hyperinsulinemia, and peripheral insulin resistance.
McKenzie B, Peloquin M, Tovar A, Graves JL, Ratcliff E, Tucker K, Vo K, Greenwood K, Halioua-Haubold CL, Juarez-Salinas D. McKenzie B, et al. Among authors: peloquin m. Am J Vet Res. 2024 Apr 15;85(6):ajvr.23.11.0253. doi: 10.2460/ajvr.23.11.0253. Print 2024 Jun 1. Am J Vet Res. 2024. PMID: 38604223 Free article.
Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity.
Flaherty SE 3rd, Bezy O, Zheng W, Yan D, Li X, Jagarlapudi S, Albuquerque B, Esquejo RM, Peloquin M, Semache M, Mancini A, Kang L, Drujan D, Breitkopf SB, Griffin JD, Jean Beltran PM, Xue L, Stansfield J, Pashos E, Shakey Q, Pehmøller C, Monetti M, Birnbaum MJ, Fortin JP, Wu Z. Flaherty SE 3rd, et al. Among authors: peloquin m. Nat Commun. 2023 Jul 4;14(1):3953. doi: 10.1038/s41467-023-39597-w. Nat Commun. 2023. PMID: 37402735 Free PMC article.
Four-Year Visual Outcomes in the Protocol W Randomized Trial of Intravitreous Aflibercept for Prevention of Vision-Threatening Complications of Diabetic Retinopathy.
Maturi RK, Glassman AR, Josic K, Baker CW, Gerstenblith AT, Jampol LM, Meleth A, Martin DF, Melia M, Punjabi OS, Rofagha S, Salehi-Had H, Stockdale CR, Sun JK; DRCR Retina Network. Maturi RK, et al. JAMA. 2023 Feb 7;329(5):376-385. doi: 10.1001/jama.2022.25029. JAMA. 2023. PMID: 36749332 Free PMC article.
AMPK activation is sufficient to increase skeletal muscle glucose uptake and glycogen synthesis but is not required for contraction-mediated increases in glucose metabolism.
Esquejo RM, Albuquerque B, Sher A, Blatnik M, Wald K, Peloquin M, Delmore J, Kindt E, Li W, Young JD, Cameron K, Miller RA. Esquejo RM, et al. Among authors: peloquin m. Heliyon. 2022 Oct 14;8(10):e11091. doi: 10.1016/j.heliyon.2022.e11091. eCollection 2022 Oct. Heliyon. 2022. PMID: 36303906 Free PMC article.
BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice.
Bollinger E, Peloquin M, Libera J, Albuquerque B, Pashos E, Shipstone A, Hadjipanayis A, Sun Z, Xing G, Clasquin M, Stansfield JC, Tierney B, Gernhardt S, Siddall CP, Greizer T, Geoly FJ, Vargas SR, Gao LC, Williams G, Marshall M, Rosado A, Steppan C, Filipski KJ, Zhang BB, Miller RA, Roth Flach RJ. Bollinger E, et al. Among authors: peloquin m. Mol Metab. 2022 Dec;66:101611. doi: 10.1016/j.molmet.2022.101611. Epub 2022 Oct 8. Mol Metab. 2022. PMID: 36220546 Free PMC article.
Characterization of cachexia in the human fibrosarcoma HT-1080 mouse tumour model.
Bernardo B, Joaquim S, Garren J, Boucher M, Houle C, LaCarubba B, Qiao S, Wu Z, Esquejo RM, Peloquin M, Kim H, Breen DM. Bernardo B, et al. Among authors: peloquin m. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1813-1829. doi: 10.1002/jcsm.12618. Epub 2020 Sep 13. J Cachexia Sarcopenia Muscle. 2020. PMID: 32924335 Free PMC article.
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