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Inhibitors of serine/threonine kinases.
Lee JC, Adams JL. Lee JC, et al. Curr Opin Biotechnol. 1995 Dec;6(6):657-61. doi: 10.1016/0958-1669(95)80108-1. Curr Opin Biotechnol. 1995. PMID: 8527836 Review.
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis.
Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW, Strickler JE, McLaughlin MM, Siemens IR, Fisher SM, Livi GP, White JR, Adams JL, Young PR. Lee JC, et al. Nature. 1994 Dec 22-29;372(6508):739-46. doi: 10.1038/372739a0. Nature. 1994. PMID: 7997261
Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase.
Gallagher TF, Seibel GL, Kassis S, Laydon JT, Blumenthal MJ, Lee JC, Lee D, Boehm JC, Fier-Thompson SM, Abt JW, Soreson ME, Smietana JM, Hall RF, Garigipati RS, Bender PE, Erhard KF, Krog AJ, Hofmann GA, Sheldrake PL, McDonnell PC, Kumar S, Young PR, Adams JL. Gallagher TF, et al. Among authors: lee d, lee jc. Bioorg Med Chem. 1997 Jan;5(1):49-64. doi: 10.1016/s0968-0896(96)00212-x. Bioorg Med Chem. 1997. PMID: 9043657
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site.
Young PR, McLaughlin MM, Kumar S, Kassis S, Doyle ML, McNulty D, Gallagher TF, Fisher S, McDonnell PC, Carr SA, Huddleston MJ, Seibel G, Porter TG, Livi GP, Adams JL, Lee JC. Young PR, et al. Among authors: lee jc. J Biol Chem. 1997 May 2;272(18):12116-21. doi: 10.1074/jbc.272.18.12116. J Biol Chem. 1997. PMID: 9115281 Free article.
4,968 results