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An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys.
Reimann KA, Li JT, Voss G, Lekutis C, Tenner-Racz K, Racz P, Lin W, Montefiori DC, Lee-Parritz DE, Lu Y, Collman RG, Sodroski J, Letvin NL. Reimann KA, et al. Among authors: lu y. J Virol. 1996 May;70(5):3198-206. doi: 10.1128/JVI.70.5.3198-3206.1996. J Virol. 1996. PMID: 8627800 Free PMC article.
Utility of SHIV for testing HIV-1 vaccine candidates in macaques.
Lu Y, Salvato MS, Pauza CD, Li J, Sodroski J, Manson K, Wyand M, Letvin N, Jenkins S, Touzjian N, Chutkowski C, Kushner N, LeFaile M, Payne LG, Roberts B. Lu Y, et al. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Jun 1;12(2):99-106. doi: 10.1097/00042560-199606010-00001. J Acquir Immune Defic Syndr Hum Retrovirol. 1996. PMID: 8680896
The T open reading frame of human immunodeficiency virus type 1.
Cohen EA, Lu Y, Göttlinger H, Dehni G, Jalinoos Y, Sodroski JG, Haseltine WA. Cohen EA, et al. Among authors: lu y. J Acquir Immune Defic Syndr (1988). 1990;3(6):601-8. J Acquir Immune Defic Syndr (1988). 1990. PMID: 2338618
In vivo replication capacity rather than in vitro macrophage tropism predicts efficiency of vaginal transmission of simian immunodeficiency virus or simian/human immunodeficiency virus in rhesus macaques.
Miller CJ, Marthas M, Greenier J, Lu D, Dailey PJ, Lu Y. Miller CJ, et al. Among authors: lu y, lu d. J Virol. 1998 Apr;72(4):3248-58. doi: 10.1128/JVI.72.4.3248-3258.1998. J Virol. 1998. PMID: 9525652 Free PMC article.
In addition, SHIV HXBc2, which replicates in monkey macrophages, does not infect rhesus macaques following multiple vaginal inoculations, while T-cell-tropic SHIV 89.6 does (Y. Lu, P. B. Brosio, M. Lafaile, J. Li, R. G. Collman, J. Sodroski, and C. J. Miller, J. ...
In addition, SHIV HXBc2, which replicates in monkey macrophages, does not infect rhesus macaques following multiple vaginal inoculations, wh …
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