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Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB. Preston S, et al. Among authors: mcgee sl. FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7. FASEB J. 2017. PMID: 28687609
This study highlights the dynamic biologic response of multicellular organisms to deguelin perturbation.-Preston, S., Korhonen, P. K., Mouchiroud, L., Cornaglia, M., McGee, S. L., Young, N. D., Davis, R. A., Crawford, S., Nowell, C., Ansell, B. R. E., …
This study highlights the dynamic biologic response of multicellular organisms to deguelin perturbation.-Preston, S., Korhonen, P. K. …
Identification of Fromiamycalin and Halaminol A from Australian Marine Sponge Extracts with Anthelmintic Activity against Haemonchus contortus.
Herath HMPD, Preston S, Jabbar A, Garcia-Bustos J, Taki AC, Addison RS, Hayes S, Beattie KD, McGee SL, Martin SD, Ekins MG, Hooper JNA, Chang BCH, Hofmann A, Davis RA, Gasser RB. Herath HMPD, et al. Among authors: mcgee sl. Mar Drugs. 2019 Oct 23;17(11):598. doi: 10.3390/md17110598. Mar Drugs. 2019. PMID: 31652835 Free PMC article.
1-Methyl-1H-pyrazole-5-carboxamide Derivatives Exhibit Unexpected Acute Mammalian Toxicity.
Preston S, Garcia-Bustos J, Hall LG, Martin SD, Le TG, Kundu A, Ghoshal A, Nguyen NH, Jiao Y, Ruan B, Xue L, Huang F, Chang BCH, McGee SL, Wells TNC, Palmer MJ, Jabbar A, Gasser RB, Baell JB. Preston S, et al. Among authors: mcgee sl. J Med Chem. 2021 Jan 14;64(1):840-844. doi: 10.1021/acs.jmedchem.0c01793. Epub 2020 Dec 22. J Med Chem. 2021. PMID: 33352050
Arylpyrrole and fipronil analogues that inhibit the motility and/or development of Haemonchus contortus in vitro.
Dilrukshi Herath HMP, Song H, Preston S, Jabbar A, Wang T, McGee SL, Hofmann A, Garcia-Bustos J, Chang BCH, Koehler AV, Liu Y, Ma Q, Zhang P, Zhao Q, Wang Q, Gasser RB. Dilrukshi Herath HMP, et al. Among authors: mcgee sl. Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):379-385. doi: 10.1016/j.ijpddr.2018.06.002. Epub 2018 Jun 4. Int J Parasitol Drugs Drug Resist. 2018. PMID: 30081296 Free PMC article.
Lysine post-translational modification of glyceraldehyde-3-phosphate dehydrogenase regulates hepatic and systemic metabolism.
Bond ST, Howlett KF, Kowalski GM, Mason S, Connor T, Cooper A, Streltsov V, Bruce CR, Walder KR, McGee SL. Bond ST, et al. Among authors: mcgee sl. FASEB J. 2017 Jun;31(6):2592-2602. doi: 10.1096/fj.201601215R. Epub 2017 Mar 3. FASEB J. 2017. PMID: 28258188
These findings show that post-translational modification of GAPDH lysine residues regulates hepatic and systemic metabolism, revealing an unappreciated role for hepatic GAPDH in substrate selection and utilization.-Bond, S. T., Howlett, K. F., Kowalski, G. M., Mason, S …
These findings show that post-translational modification of GAPDH lysine residues regulates hepatic and systemic metabolism, revealing an un …
521 results