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Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 2. Identification of (S)-N-(1-phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide (SB 223412).
Giardina GA, Raveglia LF, Grugni M, Sarau HM, Farina C, Medhurst AD, Graziani D, Schmidt DB, Rigolio R, Luttmann M, Cavagnera S, Foley JJ, Vecchietti V, Hay DW. Giardina GA, et al. Among authors: foley jj. J Med Chem. 1999 Mar 25;42(6):1053-65. doi: 10.1021/jm980633c. J Med Chem. 1999. PMID: 10090788
Nonpeptide tachykinin receptor antagonists. II. Pharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potent and selective NK-3 receptor antagonist.
Sarau HM, Griswold DE, Bush B, Potts W, Sandhu P, Lundberg D, Foley JJ, Schmidt DB, Webb EF, Martin LD, Legos JJ, Whitmore RG, Barone FC, Medhurst AD, Luttmann MA, Giardina GA, Hay DW. Sarau HM, et al. Among authors: foley jj. J Pharmacol Exp Ther. 2000 Oct;295(1):373-81. J Pharmacol Exp Ther. 2000. PMID: 10992004
Aminoalkoxybenzyl pyrrolidines as novel human urotensin-II receptor antagonists.
Jin J, Dhanak D, Knight SD, Widdowson K, Aiyar N, Naselsky D, Sarau HM, Foley JJ, Schmidt DB, Bennett CD, Wang B, Warren GL, Moore ML, Keenan RM, Rivero RA, Douglas SA. Jin J, et al. Among authors: foley jj. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3229-32. doi: 10.1016/j.bmcl.2005.04.074. Bioorg Med Chem Lett. 2005. PMID: 15936190
132 results