Hand EL - Search Results

1

Nonpeptide glycoprotein IIb/IIIa inhibitors. 8. Antiplatelet activity and oral antithrombotic efficacy of L-734,217.

Cook JJ, Holahan MA, Lyle EA, Ramjit DR, Sitko GR, Stranieri MT, Stupienski RF 3rd, Wallace AA, Hand EL, Gehret JR, Kothstein T, Drag MD, McCormick GY, Perkins JJ, Ihle NC, Duggan ME, Hartman GD, Gould RJ, Lynch JJ Jr. Cook JJ, et al. Among authors: hand el. J Pharmacol Exp Ther. 1996 Jul;278(1):62-73. J Pharmacol Exp Ther. 1996. PMID: 8764336

2

Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men.

Barrett JS, Murphy G, Peerlinck K, De Lepeleire I, Gould RJ, Panebianco D, Hand E, Deckmyn H, Vermylen J, Arnout J. Barrett JS, et al. Clin Pharmacol Ther. 1994 Oct;56(4):377-88. doi: 10.1038/clpt.1994.152. Clin Pharmacol Ther. 1994. PMID: 7955799 Clinical Trial.

3

Effects of pentobarbital on pharmacokinetics and pharmacodynamics of a potent fibrinogen receptor antagonist, L-734,217, in dogs.

Prueksaritanont T, Stranieri MT, Hand EL, Ellis JD, Holahan MA, Sitko GR, Cook JJ. Prueksaritanont T, et al. Among authors: hand el. Biopharm Drug Dispos. 1997 Nov;18(8):649-63. doi: 10.1002/(sici)1099-081x(199711)18:8<649::aid-bdd51>3.0.co;2-t. Biopharm Drug Dispos. 1997. PMID: 9373723

4

Nonpeptide glycoprotein IIb/IIIa inhibitors: 14: oral antithrombotic efficacy of L-738,167 in a conscious canine model of coronary artery electrolytic injury.

Cook JJ, Glass JD, Sitko GR, Holahan MA, Stupienski RF 3rd, Wallace AA, Stump GL, Hand EL, Askew BC, Hartman GD, Gould RJ, Lynch JJ Jr. Cook JJ, et al. Among authors: hand el. Circulation. 1997 Aug 5;96(3):949-58. Circulation. 1997. PMID: 9264506

5

Antiplatelet effects of MK-852, a platelet fibrinogen receptor antagonist, in healthy volunteers.

Greenberg HE, Wissel P, Barrett J, Barchowsky A, Gould R, Farrell D, Panebianco D, Hand E, Gillen L, Goldberg MR, Bjornsson TD. Greenberg HE, et al. J Clin Pharmacol. 2000 May;40(5):496-507. doi: 10.1177/00912700022009116. J Clin Pharmacol. 2000. PMID: 10806603 Clinical Trial.

6

MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man.

Peerlinck K, De Lepeleire I, Goldberg M, Farrell D, Barrett J, Hand E, Panebianco D, Deckmyn H, Vermylen J, Arnout J. Peerlinck K, et al. Circulation. 1993 Oct;88(4 Pt 1):1512-7. doi: 10.1161/01.cir.88.4.1512. Circulation. 1993. PMID: 8403299 Clinical Trial.

7

Determination of MK-383, a non-peptide fibrinogen receptor antagonist, in human plasma and urine by radioimmunoassay.

Hand EL, Gilbert JD, Yuan AS, Olah TV, Hichens M. Hand EL, et al. J Pharm Biomed Anal. 1994 Aug;12(8):1047-53. doi: 10.1016/0731-7085(94)e0009-p. J Pharm Biomed Anal. 1994. PMID: 7819379

8

Use of LC-MS/MS to cross-validate a radioimmunoassay for the fibrinogen receptor antagonist, Aggrastat (tirofiban hydrochloride) in human plasma.

Ellis JD, Hand EL, Gilbert JD. Ellis JD, et al. Among authors: hand el. J Pharm Biomed Anal. 1997 Feb;15(5):561-9. doi: 10.1016/s0731-7085(96)01848-1. J Pharm Biomed Anal. 1997. PMID: 9127267

9

Determination of MK-852, a new fibrinogen receptor antagonist, in plasma and urine by radioimmunoassay.

Yuan AS, Hand EL, Hichens M, Olah TV, Barrish A, Fernandez-Metzler C, Gilbert JD. Yuan AS, et al. Among authors: hand el. J Pharm Biomed Anal. 1993 Jun;11(6):427-34. doi: 10.1016/0731-7085(93)80153-r. J Pharm Biomed Anal. 1993. PMID: 8399513

10

Determination of L-365,260, a new cholecystokinin receptor (CCK-B) antagonist, in plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry.

Gilbert JD, Hand EL, Yuan AS, Olah TV, Covey TR. Gilbert JD, et al. Among authors: hand el. Biol Mass Spectrom. 1992 Feb;21(2):63-8. doi: 10.1002/bms.1200210202. Biol Mass Spectrom. 1992. PMID: 1606183

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