Summers MF - Search Results

1

Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors.

Rice WG, Turpin JA, Schaeffer CA, Graham L, Clanton D, Buckheit RW Jr, Zaharevitz D, Summers MF, Wallqvist A, Covell DG. Rice WG, et al. Among authors: summers mf. J Med Chem. 1996 Sep 13;39(19):3606-16. doi: 10.1021/jm960375o. J Med Chem. 1996. PMID: 8809151

2

Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds.

Rice WG, Schaeffer CA, Harten B, Villinger F, South TL, Summers MF, Henderson LE, Bess JW Jr, Arthur LO, McDougal JS, et al. Rice WG, et al. Among authors: summers mf. Nature. 1993 Feb 4;361(6411):473-5. doi: 10.1038/361473a0. Nature. 1993. PMID: 8429889

3

Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.

Rice WG, Turpin JA, Huang M, Clanton D, Buckheit RW Jr, Covell DG, Wallqvist A, McDonnell NB, DeGuzman RN, Summers MF, Zalkow L, Bader JP, Haugwitz RD, Sausville EA. Rice WG, et al. Among authors: summers mf. Nat Med. 1997 Mar;3(3):341-5. doi: 10.1038/nm0397-341. Nat Med. 1997. PMID: 9055865

4

Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.

McDonnell NB, De Guzman RN, Rice WG, Turpin JA, Summers MF. McDonnell NB, et al. Among authors: summers mf. J Med Chem. 1997 Jun 20;40(13):1969-76. doi: 10.1021/jm970147+. J Med Chem. 1997. PMID: 9207937

5

Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1.

Summers MF, Henderson LE, Chance MR, Bess JW Jr, South TL, Blake PR, Sagi I, Perez-Alvarado G, Sowder RC 3rd, Hare DR, et al. Summers MF, et al. Protein Sci. 1992 May;1(5):563-74. doi: 10.1002/pro.5560010502. Protein Sci. 1992. PMID: 1304355 Free PMC article.

6

NMR and computational evidence that high-affinity bradykinin receptor antagonists adopt C-terminal beta-turns.

Kyle DJ, Blake PR, Smithwick D, Green LM, Martin JA, Sinsko JA, Summers MF. Kyle DJ, et al. Among authors: summers mf. J Med Chem. 1993 May 14;36(10):1450-60. doi: 10.1021/jm00062a018. J Med Chem. 1993. PMID: 8388469

7

Zinc- and sequence-dependent binding to nucleic acids by the N-terminal zinc finger of the HIV-1 nucleocapsid protein: NMR structure of the complex with the Psi-site analog, dACGCC.

South TL, Summers MF. South TL, et al. Among authors: summers mf. Protein Sci. 1993 Jan;2(1):3-19. doi: 10.1002/pro.5560020102. Protein Sci. 1993. PMID: 8443588 Free PMC article.

8

Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1.

Ku T, Lopresti N, Shirley M, Mori M, Marchant J, Heng X, Botta M, Summers MF, Seley-Radtke KL. Ku T, et al. Among authors: summers mf. Bioorg Med Chem. 2019 Jul 1;27(13):2883-2892. doi: 10.1016/j.bmc.2019.05.019. Epub 2019 May 15. Bioorg Med Chem. 2019. PMID: 31126822 Free PMC article.

9

Zinc finger motif for single-stranded nucleic acids? Investigations by nuclear magnetic resonance.

Summers MF. Summers MF. J Cell Biochem. 1991 Jan;45(1):41-8. doi: 10.1002/jcb.240450110. J Cell Biochem. 1991. PMID: 2005183 Review.

10

C-terminal retroviral-type zinc finger domain from the HIV-1 nucleocapsid protein is structurally similar to the N-terminal zinc finger domain.

South TL, Blake PR, Hare DR, Summers MF. South TL, et al. Among authors: summers mf. Biochemistry. 1991 Jun 25;30(25):6342-9. doi: 10.1021/bi00239a036. Biochemistry. 1991. PMID: 2059638

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