Turpin JA - Search Results

1

Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors.

Rice WG, Turpin JA, Schaeffer CA, Graham L, Clanton D, Buckheit RW Jr, Zaharevitz D, Summers MF, Wallqvist A, Covell DG. Rice WG, et al. Among authors: turpin ja. J Med Chem. 1996 Sep 13;39(19):3606-16. doi: 10.1021/jm960375o. J Med Chem. 1996. PMID: 8809151

2

Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: a candidate for chemotherapeutic and microbicidal application.

Howard OM, Oppenheim JJ, Hollingshead MG, Covey JM, Bigelow J, McCormack JJ, Buckheit RW Jr, Clanton DJ, Turpin JA, Rice WG. Howard OM, et al. Among authors: turpin ja. J Med Chem. 1998 Jun 18;41(13):2184-93. doi: 10.1021/jm9801253. J Med Chem. 1998. PMID: 9632350

3

Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.

Turpin JA, Song Y, Inman JK, Huang M, Wallqvist A, Maynard A, Covell DG, Rice WG, Appella E. Turpin JA, et al. J Med Chem. 1999 Jan 14;42(1):67-86. doi: 10.1021/jm9802517. J Med Chem. 1999. PMID: 9888834

4

Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.

McDonnell NB, De Guzman RN, Rice WG, Turpin JA, Summers MF. McDonnell NB, et al. Among authors: turpin ja. J Med Chem. 1997 Jun 20;40(13):1969-76. doi: 10.1021/jm970147+. J Med Chem. 1997. PMID: 9207937

5

Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.

Huang M, Maynard A, Turpin JA, Graham L, Janini GM, Covell DG, Rice WG. Huang M, et al. Among authors: turpin ja. J Med Chem. 1998 Apr 23;41(9):1371-81. doi: 10.1021/jm9708543. J Med Chem. 1998. PMID: 9554870

6

Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS.

Rice WG, Supko JG, Malspeis L, Buckheit RW Jr, Clanton D, Bu M, Graham L, Schaeffer CA, Turpin JA, Domagala J, Gogliotti R, Bader JP, Halliday SM, Coren L, Sowder RC 2nd, Arthur LO, Henderson LE. Rice WG, et al. Among authors: turpin ja. Science. 1995 Nov 17;270(5239):1194-7. doi: 10.1126/science.270.5239.1194. Science. 1995. PMID: 7502043

7

Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.

Rice WG, Baker DC, Schaeffer CA, Graham L, Bu M, Terpening S, Clanton D, Schultz R, Bader JP, Buckheit RW Jr, Field L, Singh PK, Turpin JA. Rice WG, et al. Among authors: turpin ja. Antimicrob Agents Chemother. 1997 Feb;41(2):419-26. doi: 10.1128/AAC.41.2.419. Antimicrob Agents Chemother. 1997. PMID: 9021201 Free PMC article.

8

Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.

Rice WG, Turpin JA, Huang M, Clanton D, Buckheit RW Jr, Covell DG, Wallqvist A, McDonnell NB, DeGuzman RN, Summers MF, Zalkow L, Bader JP, Haugwitz RD, Sausville EA. Rice WG, et al. Among authors: turpin ja. Nat Med. 1997 Mar;3(3):341-5. doi: 10.1038/nm0397-341. Nat Med. 1997. PMID: 9055865

9

Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles.

Turpin JA, Terpening SJ, Schaeffer CA, Yu G, Glover CJ, Felsted RL, Sausville EA, Rice WG. Turpin JA, et al. J Virol. 1996 Sep;70(9):6180-9. doi: 10.1128/JVI.70.9.6180-6189.1996. J Virol. 1996. PMID: 8709244 Free PMC article.

10

Small molecule inhibitor of HIV-1 cell fusion blocks chemokine receptor-mediated function.

Howard OM, Korte T, Tarasova NI, Grimm M, Turpin JA, Rice WG, Michejda CJ, Blumenthal R, Oppenheim JJ. Howard OM, et al. Among authors: turpin ja. J Leukoc Biol. 1998 Jul;64(1):6-13. doi: 10.1002/jlb.64.1.6. J Leukoc Biol. 1998. PMID: 9665268 Review.

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