Keyt BA - Search Results

1

Limiting systemic plasminogenolysis reduces the bleeding potential for tissue-type plasminogen activators but not for streptokinase.

Thomas GR, Thibodeaux H, Errett CJ, Badillo JM, Wu DT, Refino CJ, Keyt BA, Bennett WF. Thomas GR, et al. Among authors: keyt ba. Thromb Haemost. 1996 Jun;75(6):915-20. Thromb Haemost. 1996. PMID: 8822586

2

A long-half-life and fibrin-specific form of tissue plasminogen activator in rabbit models of embolic stroke and peripheral bleeding.

Thomas GR, Thibodeaux H, Errett CJ, Badillo JM, Keyt BA, Refino CJ, Zivin JA, Bennett WF. Thomas GR, et al. Among authors: keyt ba. Stroke. 1994 Oct;25(10):2072-8; discussion 2078-9. doi: 10.1161/01.str.25.10.2072. Stroke. 1994. PMID: 8091454

3

A faster-acting and more potent form of tissue plasminogen activator.

Keyt BA, Paoni NF, Refino CJ, Berleau L, Nguyen H, Chow A, Lai J, Peña L, Pater C, Ogez J, et al. Keyt BA, et al. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3670-4. doi: 10.1073/pnas.91.9.3670. Proc Natl Acad Sci U S A. 1994. PMID: 8170967 Free PMC article.

4

A slow clearing, fibrin-specific, PAI-1 resistant variant of t-PA (T103N, KHRR 296-299 AAAA).

Paoni NF, Keyt BA, Refino CJ, Chow AM, Nguyen HV, Berleau LT, Badillo J, Peña LC, Brady K, Wurm FM, et al. Paoni NF, et al. Among authors: keyt ba. Thromb Haemost. 1993 Aug 2;70(2):307-12. Thromb Haemost. 1993. PMID: 8236140

5

A variant of t-PA (T103N, KHRR 296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen.

Refino CJ, Paoni NF, Keyt BA, Pater CS, Badillo JM, Wurm FM, Ogez J, Bennett WF. Refino CJ, et al. Among authors: keyt ba. Thromb Haemost. 1993 Aug 2;70(2):313-9. Thromb Haemost. 1993. PMID: 8236141

6

Comparative thrombolytic properties of tissue-type plasminogen activator and of a plasminogen activator inhibitor-1-resistant glycosylation variant, in a combined arterial and venous thrombosis model in the dog.

Collen D, Stassen JM, Yasuda T, Refino C, Paoni N, Keyt B, Roskams T, Guerrero JL, Lijnen HR, Gold HK, et al. Collen D, et al. Thromb Haemost. 1994 Jul;72(1):98-104. Thromb Haemost. 1994. PMID: 7974384

7

Radioiodination of the active site of tissue plasminogen activator: a method for radiolabeling serine proteases with tyrosylprolylarginyl chloromethyl ketone.

Keyt BA, Berleau LT, Nguyen HV, Bennett WF. Keyt BA, et al. Anal Biochem. 1992 Oct;206(1):73-83. doi: 10.1016/s0003-2697(05)80013-2. Anal Biochem. 1992. PMID: 1456445

8

High resolution analysis of functional determinants on human tissue-type plasminogen activator.

Bennett WF, Paoni NF, Keyt BA, Botstein D, Jones AJ, Presta L, Wurm FM, Zoller MJ. Bennett WF, et al. Among authors: keyt ba. J Biol Chem. 1991 Mar 15;266(8):5191-201. J Biol Chem. 1991. PMID: 1900516 Free article.

9

New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA.

Benedict CR, Refino CJ, Keyt BA, Pakala R, Paoni NF, Thomas GR, Bennett WF. Benedict CR, et al. Among authors: keyt ba. Circulation. 1995 Nov 15;92(10):3032-40. doi: 10.1161/01.cir.92.10.3032. Circulation. 1995. PMID: 7586274

10

Making tissue-type plasminogen activator more fibrin specific.

Paoni NF, Chow AM, Peña LC, Keyt BA, Zoller MJ, Bennett WF. Paoni NF, et al. Among authors: keyt ba. Protein Eng. 1993 Jul;6(5):529-34. doi: 10.1093/protein/6.5.529. Protein Eng. 1993. PMID: 8415579

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