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Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.
Rhoades KL, Hetherington CJ, Rowley JD, Hiebert SW, Nucifora G, Tenen DG, Zhang DE. Rhoades KL, et al. Among authors: hetherington cj. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11895-900. doi: 10.1073/pnas.93.21.11895. Proc Natl Acad Sci U S A. 1996. PMID: 8876234 Free PMC article.
C/EBPbeta is required for 'emergency' granulopoiesis.
Hirai H, Zhang P, Dayaram T, Hetherington CJ, Mizuno S, Imanishi J, Akashi K, Tenen DG. Hirai H, et al. Among authors: hetherington cj. Nat Immunol. 2006 Jul;7(7):732-9. doi: 10.1038/ni1354. Epub 2006 Jun 4. Nat Immunol. 2006. PMID: 16751774
PU.1 (Spi-1) autoregulates its expression in myeloid cells.
Chen H, Ray-Gallet D, Zhang P, Hetherington CJ, Gonzalez DA, Zhang DE, Moreau-Gachelin F, Tenen DG. Chen H, et al. Among authors: hetherington cj. Oncogene. 1995 Oct 19;11(8):1549-60. Oncogene. 1995. PMID: 7478579
42 results