Michiels F - Search Results

1

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.

Michiels F, Stam JC, Hordijk PL, van der Kammen RA, Ruuls-Van Stalle L, Feltkamp CA, Collard JG. Michiels F, et al. J Cell Biol. 1997 Apr 21;137(2):387-98. doi: 10.1083/jcb.137.2.387. J Cell Biol. 1997. PMID: 9128250 Free PMC article.

2

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

Malliri A, van der Kammen RA, Clark K, van der Valk M, Michiels F, Collard JG. Malliri A, et al. Among authors: michiels f. Nature. 2002 Jun 20;417(6891):867-71. doi: 10.1038/nature00848. Nature. 2002. PMID: 12075356

3

Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.

Ten Klooster JP, Evers EE, Janssen L, Machesky LM, Michiels F, Hordijk P, Collard JG. Ten Klooster JP, et al. Among authors: michiels f. Biochem J. 2006 Jul 1;397(1):39-45. doi: 10.1042/BJ20051957. Biochem J. 2006. PMID: 16599904 Free PMC article.

4

The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG. Leeuwen FN, et al. Among authors: michiels f. J Cell Biol. 1997 Nov 3;139(3):797-807. doi: 10.1083/jcb.139.3.797. J Cell Biol. 1997. PMID: 9348295 Free PMC article.

5

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain.

Stam JC, Sander EE, Michiels F, van Leeuwen FN, Kain HE, van der Kammen RA, Collard JG. Stam JC, et al. Among authors: michiels f. J Biol Chem. 1997 Nov 7;272(45):28447-54. doi: 10.1074/jbc.272.45.28447. J Biol Chem. 1997. PMID: 9353304 Free article.

6

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling.

Hordijk PL, ten Klooster JP, van der Kammen RA, Michiels F, Oomen LC, Collard JG. Hordijk PL, et al. Among authors: michiels f. Science. 1997 Nov 21;278(5342):1464-6. doi: 10.1126/science.278.5342.1464. Science. 1997. PMID: 9367959

7

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling.

Stam JC, Michiels F, van der Kammen RA, Moolenaar WH, Collard JG. Stam JC, et al. Among authors: michiels f. EMBO J. 1998 Jul 15;17(14):4066-74. doi: 10.1093/emboj/17.14.4066. EMBO J. 1998. PMID: 9670021 Free PMC article.

8

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase.

Sander EE, van Delft S, ten Klooster JP, Reid T, van der Kammen RA, Michiels F, Collard JG. Sander EE, et al. Among authors: michiels f. J Cell Biol. 1998 Nov 30;143(5):1385-98. doi: 10.1083/jcb.143.5.1385. J Cell Biol. 1998. PMID: 9832565 Free PMC article.

9

Rho-like GTPases: their role in cell adhesion and invasion.

Michiels F, Collard JG. Michiels F, et al. Biochem Soc Symp. 1999;65:125-46. Biochem Soc Symp. 1999. PMID: 10320937 Review.

10

Sequence of the human invasion-inducing TIAM1 gene, its conservation in evolution and its expression in tumor cell lines of different tissue origin.

Habets GG, van der Kammen RA, Stam JC, Michiels F, Collard JG. Habets GG, et al. Among authors: michiels f. Oncogene. 1995 Apr 6;10(7):1371-6. Oncogene. 1995. PMID: 7731688

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