Grob PM - Search Results

1

Prophylaxis against HIV-1 infection in chimpanzees by nevirapine, a nonnucleoside inhibitor of reverse transcriptase.

Grob PM, Cao Y, Muchmore E, Ho DD, Norris S, Pav JW, Shih CK, Adams J. Grob PM, et al. Nat Med. 1997 Jun;3(6):665-70. doi: 10.1038/nm0697-665. Nat Med. 1997. PMID: 9176494

2

Nonnucleoside inhibitors of HIV-1 reverse transcriptase: nevirapine as a prototype drug.

Grob PM, Wu JC, Cohen KA, Ingraham RH, Shih CK, Hargrave KD, McTague TL, Merluzzi VJ. Grob PM, et al. AIDS Res Hum Retroviruses. 1992 Feb;8(2):145-52. doi: 10.1089/aid.1992.8.145. AIDS Res Hum Retroviruses. 1992. PMID: 1371691 Review.

3

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl-dipyridodiazepinones.

Kelly TA, McNeil DW, Rose JM, David E, Shih CK, Grob PM. Kelly TA, et al. Among authors: grob pm. J Med Chem. 1997 Jul 18;40(15):2430-3. doi: 10.1021/jm960837y. J Med Chem. 1997. PMID: 9240358

4

Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 7. 8-Arylethyldipyridodiazepinones as potent broad-spectrum inhibitors of wild-type and mutant enzymes.

Klunder JM, Hoermann M, Cywin CL, David E, Brickwood JR, Schwartz R, Barringer KJ, Pauletti D, Shih CK, Erickson DA, Sorge CL, Joseph DP, Hattox SE, Adams J, Grob PM. Klunder JM, et al. Among authors: grob pm. J Med Chem. 1998 Jul 30;41(16):2960-71. doi: 10.1021/jm9707028. J Med Chem. 1998. PMID: 9685235

5

A novel dipyridodiazepinone inhibitor of HIV-1 reverse transcriptase acts through a nonsubstrate binding site.

Wu JC, Warren TC, Adams J, Proudfoot J, Skiles J, Raghavan P, Perry C, Potocki I, Farina PR, Grob PM. Wu JC, et al. Among authors: grob pm. Biochemistry. 1991 Feb 26;30(8):2022-6. doi: 10.1021/bi00222a003. Biochemistry. 1991. PMID: 1705436

6

Steady state kinetics and inhibition of HIV-1 reverse transcriptase by a non-nucleoside dipyridodiazepinone, BI-RG-587, using a heteropolymeric template.

Kopp EB, Miglietta JJ, Shrutkowski AG, Shih CK, Grob PM, Skoog MT. Kopp EB, et al. Among authors: grob pm. Nucleic Acids Res. 1991 Jun 11;19(11):3035-9. doi: 10.1093/nar/19.11.3035. Nucleic Acids Res. 1991. PMID: 1711678 Free PMC article.

7

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 5. 4-Substituted and 2,4-disubstituted analogs of nevirapine.

Kelly TA, Proudfoot JR, McNeil DW, Patel UR, David E, Hargrave KD, Grob PM, Cardozo M, Agarwal A, Adams J. Kelly TA, et al. Among authors: grob pm. J Med Chem. 1995 Nov 24;38(24):4839-47. doi: 10.1021/jm00024a011. J Med Chem. 1995. PMID: 7490733

8

Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 8. 8-Aryloxymethyl- and 8-arylthiomethyldipyridodiazepinones.

Cywin CL, Klunder JM, Hoermann M, Brickwood JR, David E, Grob PM, Schwartz R, Pauletti D, Barringer KJ, Shih CK, Sorge CL, Erickson DA, Joseph DP, Hattox SE. Cywin CL, et al. Among authors: grob pm. J Med Chem. 1998 Jul 30;41(16):2972-84. doi: 10.1021/jm9707030. J Med Chem. 1998. PMID: 9685236

9

High-performance liquid chromatography and photoaffinity crosslinking to explore the binding environment of nevirapine to reverse transcriptase of human immunodeficiency virus.

Palladino DE, Hopkins JL, Ingraham RH, Warren TC, Kapadia SR, Van Moffaert GJ, Grob PM, Stevenson JM, Cohen KA. Palladino DE, et al. Among authors: grob pm. J Chromatogr A. 1994 Jul 29;676(1):99-112. doi: 10.1016/0021-9673(94)80458-3. J Chromatogr A. 1994. PMID: 7522840

10

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.

Pargellis C, Tong L, Churchill L, Cirillo PF, Gilmore T, Graham AG, Grob PM, Hickey ER, Moss N, Pav S, Regan J. Pargellis C, et al. Among authors: grob pm. Nat Struct Biol. 2002 Apr;9(4):268-72. doi: 10.1038/nsb770. Nat Struct Biol. 2002. PMID: 11896401

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