Melacini G - Search Results

1

Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies.

Osapay G, Prokai L, Kim HS, Medzihradszky KF, Coy DH, Liapakis G, Reisine T, Melacini G, Zhu Q, Wang SH, Mattern RH, Goodman M. Osapay G, et al. Among authors: melacini g. J Med Chem. 1997 Jul 4;40(14):2241-51. doi: 10.1021/jm960850i. J Med Chem. 1997. PMID: 9216843

2

QSAR models reveal new EPAC-selective allosteric modulators.

Mohamed H, Shao H, Akimoto M, Darveau P, MacKinnon MR, Magolan J, Melacini G. Mohamed H, et al. Among authors: melacini g. RSC Chem Biol. 2022 Aug 3;3(10):1230-1239. doi: 10.1039/d2cb00106c. eCollection 2022 Oct 5. RSC Chem Biol. 2022. PMID: 36320893 Free PMC article.

3

Toward a molecular mechanism for the interaction of ATP with alpha-synuclein.

Kamski-Hennekam ER, Huang J, Ahmed R, Melacini G. Kamski-Hennekam ER, et al. Among authors: melacini g. Chem Sci. 2023 Aug 26;14(36):9933-9942. doi: 10.1039/d3sc03612j. eCollection 2023 Sep 20. Chem Sci. 2023. PMID: 37736631 Free PMC article.

4

Fractionation factors reveal hidden frustration in an ancient allosteric module.

VanSchouwen B, Della Libera L, Melacini G. VanSchouwen B, et al. Among authors: melacini g. J Chem Phys. 2023 Mar 28;158(12):121101. doi: 10.1063/5.0139510. J Chem Phys. 2023. PMID: 37003757

5

Probing ligand selectivity in pathogens.

VanSchouwen B, Melacini G. VanSchouwen B, et al. Among authors: melacini g. Elife. 2023 Dec 21;12:e94720. doi: 10.7554/eLife.94720. Elife. 2023. PMID: 38126364 Free PMC article.

6

Early-Onset Parkinson Mutation Remodels Monomer-Fibril Interactions to Allosterically Amplify Synuclein's Amyloid Cascade.

Huang J, Ahmed R, Akimoto M, Martinez Pomier K, Melacini G. Huang J, et al. Among authors: melacini g. JACS Au. 2023 Dec 13;3(12):3485-3493. doi: 10.1021/jacsau.3c00655. eCollection 2023 Dec 25. JACS Au. 2023. PMID: 38155658 Free PMC article.

7

Collagen-based structures containing the peptoid residue N-isobutylglycine (Nleu): synthesis and biophysical studies of Gly-Pro-Nleu sequences by circular dichroism, ultraviolet absorbance, and optical rotation.

Feng Y, Melacini G, Taulane JP, Goodman M. Feng Y, et al. Among authors: melacini g. Biopolymers. 1996 Dec;39(6):859-72. doi: 10.1002/(SICI)1097-0282(199612)39:6%3C859::AID-BIP10%3E3.0.CO;2-Z. Biopolymers. 1996. PMID: 8946805

8

Multiconformational NMR analysis of sandostatin (octreotide): equilibrium between beta-sheet and partially helical structures.

Melacini G, Zhu Q, Goodman M. Melacini G, et al. Biochemistry. 1997 Feb 11;36(6):1233-41. doi: 10.1021/bi962497o. Biochemistry. 1997. PMID: 9063871

9

A refined model for the somatostatin pharmacophore: conformational analysis of lanthionine-sandostatin analogs.

Melacini G, Zhu Q, Osapay G, Goodman M. Melacini G, et al. J Med Chem. 1997 Jul 4;40(14):2252-8. doi: 10.1021/jm960851a. J Med Chem. 1997. PMID: 9216844

10

Collagen-based structures containing the peptoid residue N-isobutylglycine (Nleu): synthesis and biophysical studies of Gly-Nleu-Pro sequences by circular dichroism and optical rotation.

Feng Y, Melacini G, Goodman M. Feng Y, et al. Among authors: melacini g. Biochemistry. 1997 Jul 22;36(29):8716-24. doi: 10.1021/bi962980z. Biochemistry. 1997. PMID: 9220958

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