Opgenorth TJ - Search Results

1

The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley rats.

Chen SJ, Chen YF, Opgenorth TJ, Wessale JL, Meng QC, Durand J, DiCarlo VS, Oparil S. Chen SJ, et al. Among authors: opgenorth tj. J Cardiovasc Pharmacol. 1997 Jun;29(6):713-25. doi: 10.1097/00005344-199706000-00003. J Cardiovasc Pharmacol. 1997. PMID: 9234651

2

Selective antagonism of the ET(A) receptor reduces neointimal hyperplasia after balloon-induced vascular injury in pigs.

Burke SE, Lubbers NL, Gagne GD, Wessale JL, Dayton BD, Wegner CD, Opgenorth TJ. Burke SE, et al. Among authors: opgenorth tj. J Cardiovasc Pharmacol. 1997 Jul;30(1):33-41. doi: 10.1097/00005344-199707000-00006. J Cardiovasc Pharmacol. 1997. PMID: 9268219

3

Metabolic responses with endothelin antagonism in a model of insulin resistance.

Berthiaume N, Wessale JL, Opgenorth TJ, Zinker BA. Berthiaume N, et al. Among authors: opgenorth tj. Metabolism. 2005 Jun;54(6):735-40. doi: 10.1016/j.metabol.2004.12.019. Metabolism. 2005. PMID: 15931607

4

Role of the endothelin system in secondary pulmonary hypertension related to air embolism: lessons learned from testing four classes of endothelin blockers in a rat model.

Battistini B, Verreault M, Ayach B, Blouin A, Cernacek P, Jeng AY, Wessale J, Opgenorth T, Tsang J. Battistini B, et al. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S386-9. doi: 10.1097/01.fjc.0000166295.18066.f8. J Cardiovasc Pharmacol. 2004. PMID: 15838327

5

Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

Opgenorth TJ, Adler AL, Calzadilla SV, Chiou WJ, Dayton BD, Dixon DB, Gehrke LJ, Hernandez L, Magnuson SR, Marsh KC, Novosad EI, Von Geldern TW, Wessale JL, Winn M, Wu-Wong JR. Opgenorth TJ, et al. J Pharmacol Exp Ther. 1996 Feb;276(2):473-81. J Pharmacol Exp Ther. 1996. PMID: 8632312

6

Pharmacology of A-216546: a highly selective antagonist for endothelin ET(A) receptor.

Wu-Wong JR, Dixon DB, Chiou WJ, Dayton BD, Novosad EI, Adler AL, Wessale JL, Calzadilla SV, Hernandez L, Marsh KC, Liu G, Szczepankiewicz B, von Geldern TW, Opgenorth TJ. Wu-Wong JR, et al. Among authors: opgenorth tj. Eur J Pharmacol. 1999 Feb 5;366(2-3):189-201. doi: 10.1016/s0014-2999(98)00891-7. Eur J Pharmacol. 1999. PMID: 10082200

7

ABT-627, an endothelin ET(A) receptor-selective antagonist, attenuates tactile allodynia in a diabetic rat model of neuropathic pain.

Jarvis MF, Wessale JL, Zhu CZ, Lynch JJ, Dayton BD, Calzadilla SV, Padley RJ, Opgenorth TJ, Kowaluk EA. Jarvis MF, et al. Among authors: opgenorth tj. Eur J Pharmacol. 2000 Jan 24;388(1):29-35. doi: 10.1016/s0014-2999(99)00865-1. Eur J Pharmacol. 2000. PMID: 10657544

8

Selective antagonism of the ETA receptor, but not the ETB receptor, is protective against ischemic acute renal failure in rats.

Kuro T, Kohnou K, Kobayashi Y, Takaoka M, Opgenorth TJ, Wessale JL, Matsumura Y. Kuro T, et al. Among authors: opgenorth tj. Jpn J Pharmacol. 2000 Apr;82(4):307-16. doi: 10.1254/jjp.82.307. Jpn J Pharmacol. 2000. PMID: 10875750 Free article.

9

'Irreversible' endothelin-1 binding does not prohibit ABT-627 from reversing endothelin-1-induced effects.

Chiou WJ, Wessale JL, von Geldern T, Opgenorth TJ, Wu-Wong JR. Chiou WJ, et al. Among authors: opgenorth tj. J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S48-52. doi: 10.1097/00005344-200036051-00017. J Cardiovasc Pharmacol. 2000. PMID: 11078333

10

Increased susceptibility to deoxycorticosterone acetate-salt-induced hypertension in endothelin-B-receptor-deficient rats.

Matsumura Y, Kuro T, Kobayashi Y, Konishi F, Takaoka M, Wessale JL, Opgenorth TJ, Gariepy CE, Yanagisawa M. Matsumura Y, et al. Among authors: opgenorth tj. J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S86-9. doi: 10.1097/00005344-200036051-00028. J Cardiovasc Pharmacol. 2000. PMID: 11078344

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