Fukushi K - Search Results

1

Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease.

Iyo M, Namba H, Fukushi K, Shinotoh H, Nagatsuka S, Suhara T, Sudo Y, Suzuki K, Irie T. Iyo M, et al. Among authors: fukushi k. Lancet. 1997 Jun 21;349(9068):1805-9. doi: 10.1016/S0140-6736(96)09124-6. Lancet. 1997. PMID: 9269216

2

Positron emission tomography: quantitative measurement of brain acetylcholinesterase activity using radiolabeled substrates.

Namba H, Fukushi K, Nagatsuka S, Iyo M, Shinotoh H, Tanada S, Irie T. Namba H, et al. Among authors: fukushi k. Methods. 2002 Jul;27(3):242-50. doi: 10.1016/s1046-2023(02)00081-6. Methods. 2002. PMID: 12183113

3

Acetylcholinesterase imaging: its use in therapy evaluation and drug design.

Shinotoh H, Fukushi K, Nagatsuka S, Irie T. Shinotoh H, et al. Among authors: fukushi k. Curr Pharm Des. 2004;10(13):1505-17. doi: 10.2174/1381612043384763. Curr Pharm Des. 2004. PMID: 15134572 Review.

4

Evaluation of simplified kinetic analyses for measurement of brain acetylcholinesterase activity using N-[11C]Methylpiperidin-4-yl propionate and positron emission tomography.

Sato K, Fukushi K, Shinotoh H, Nagatsuka S, Tanaka N, Aotsuka A, Ota T, Shiraishi T, Tanada S, Iyo M, Irie T. Sato K, et al. Among authors: fukushi k. J Cereb Blood Flow Metab. 2004 Jun;24(6):600-11. doi: 10.1097/01.WCB.0000117689.98763.6A. J Cereb Blood Flow Metab. 2004. PMID: 15181367

5

A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT.

Ota T, Shinotoh H, Fukushi K, Nagatsuka S, Namba H, Iyo M, Aotsuka A, Tanaka N, Sato K, Shiraishi T, Tanada S, Arai H, Irie T. Ota T, et al. Among authors: fukushi k. Ann Nucl Med. 2004 May;18(3):187-93. doi: 10.1007/BF02984999. Ann Nucl Med. 2004. PMID: 15233279 Clinical Trial.

6

Estimation of plasma IC50 of donepezil hydrochloride for brain acetylcholinesterase inhibition in monkey using N-[11C]methylpiperidin-4-yl acetate ([11C]MP4A) and PET.

Shiraishi T, Kikuchi T, Fukushi K, Shinotoh H, Nagatsuka S, Tanaka N, Ota T, Sato K, Hirano S, Tanada S, Iyo M, Irie T. Shiraishi T, et al. Among authors: fukushi k. Neuropsychopharmacology. 2005 Dec;30(12):2154-61. doi: 10.1038/sj.npp.1300759. Neuropsychopharmacology. 2005. PMID: 15920507

7

Estimation of plasma IC50 of donepezil for cerebral acetylcholinesterase inhibition in patients with Alzheimer disease using positron emission tomography.

Ota T, Shinotoh H, Fukushi K, Kikuchi T, Sato K, Tanaka N, Shimada H, Hirano S, Miyoshi M, Arai H, Suhara T, Irie T. Ota T, et al. Among authors: fukushi k. Clin Neuropharmacol. 2010 Mar-Apr;33(2):74-8. doi: 10.1097/WNF.0b013e3181c71be9. Clin Neuropharmacol. 2010. PMID: 19935404 Clinical Trial.

8

Voxel-Based Acetylcholinesterase PET Study in Early and Late Onset Alzheimer's Disease.

Hirano S, Shinotoh H, Shimada H, Ota T, Sato K, Tanaka N, Zhang MR, Higuchi M, Fukushi K, Irie T, Kuwabara S, Suhara T. Hirano S, et al. Among authors: fukushi k. J Alzheimers Dis. 2018;62(4):1539-1548. doi: 10.3233/JAD-170749. J Alzheimers Dis. 2018. PMID: 29562505

9

In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog.

Namba H, Irie T, Fukushi K, Iyo M. Namba H, et al. Among authors: fukushi k. Brain Res. 1994 Dec 26;667(2):278-82. doi: 10.1016/0006-8993(94)91507-5. Brain Res. 1994. PMID: 7697367

10

Evaluation of phenylmethanesulfonyl fluoride (PMSF) as a tracer candidate mapping acetylcholinesterase in vivo.

Irie T, Fukushi K, Iyo M. Irie T, et al. Among authors: fukushi k. Nucl Med Biol. 1993 Nov;20(8):991-2. doi: 10.1016/0969-8051(93)90100-9. Nucl Med Biol. 1993. PMID: 8298579

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