Costello JF - Search Results

1

Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene.

Watts GS, Pieper RO, Costello JF, Peng YM, Dalton WS, Futscher BW. Watts GS, et al. Among authors: costello jf. Mol Cell Biol. 1997 Sep;17(9):5612-9. doi: 10.1128/MCB.17.9.5612. Mol Cell Biol. 1997. PMID: 9271436 Free PMC article.

2

Direct correlation between methylation status and expression of the human O-6-methylguanine DNA methyltransferase gene.

Pieper RO, Costello JF, Kroes RA, Futscher BW, Marathi U, Erickson LC. Pieper RO, et al. Among authors: costello jf. Cancer Commun. 1991 Aug;3(8):241-53. doi: 10.3727/095535491820873092. Cancer Commun. 1991. PMID: 1716139

3

Costello JF, Futscher BW, Kroes RA, Pieper RO. Costello JF, et al. Mol Cell Biol. 1994 Oct;14(10):6515-21. doi: 10.1128/mcb.14.10.6515-6521.1994. Mol Cell Biol. 1994. PMID: 7523853 Free PMC article.

4

Graded methylation in the promoter and body of the O6-methylguanine DNA methyltransferase (MGMT) gene correlates with MGMT expression in human glioma cells.

Costello JF, Futscher BW, Tano K, Graunke DM, Pieper RO. Costello JF, et al. J Biol Chem. 1994 Jun 24;269(25):17228-37. J Biol Chem. 1994. PMID: 8006031 Free article.

5

Methylation of CpG island transcription factor binding sites is unnecessary for aberrant silencing of the human MGMT gene.

Pieper RO, Patel S, Ting SA, Futscher BW, Costello JF. Pieper RO, et al. Among authors: costello jf. J Biol Chem. 1996 Jun 7;271(23):13916-24. doi: 10.1074/jbc.271.23.13916. J Biol Chem. 1996. PMID: 8662860 Free article.

6

Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections.

Schupp PG, Shelton SJ, Brody DJ, Eliscu R, Johnson BE, Mazor T, Kelley KW, Potts MB, McDermott MW, Huang EJ, Lim DA, Pieper RO, Berger MS, Costello JF, Phillips JJ, Oldham MC. Schupp PG, et al. Among authors: costello jf. Cancers (Basel). 2024 Jul 1;16(13):2429. doi: 10.3390/cancers16132429. Cancers (Basel). 2024. PMID: 39001492 Free PMC article.

7

O6-methylguanine-DNA methyltransferase in tumors and cells of the oligodendrocyte lineage.

Nutt CL, Costello JF, Bambrick LL, Yarosh DB, Swinnen LJ, Chambers AF, Cairncross JG. Nutt CL, et al. Among authors: costello jf. Can J Neurol Sci. 1995 May;22(2):111-5. doi: 10.1017/s0317167100040178. Can J Neurol Sci. 1995. PMID: 7627911

8

Deconstructing intratumoral heterogeneity through multiomic and multiscale analysis of serial sections.

Schupp PG, Shelton SJ, Brody DJ, Eliscu R, Johnson BE, Mazor T, Kelley KW, Potts MB, McDermott MW, Huang EJ, Lim DA, Pieper RO, Berger MS, Costello JF, Phillips JJ, Oldham MC. Schupp PG, et al. Among authors: costello jf. bioRxiv [Preprint]. 2024 Mar 18:2023.06.21.545365. doi: 10.1101/2023.06.21.545365. bioRxiv. 2024. Update in: Cancers (Basel). 2024 Jul 01;16(13):2429. doi: 10.3390/cancers16132429 PMID: 37645893 Free PMC article. Updated. Preprint.

9

Longitudinal multimodal profiling of IDH-wildtype glioblastoma reveals the molecular evolution and cellular phenotypes underlying prognostically different treatment responses.

Lucas CG, Al-Adli NN, Young JS, Gupta R, Morshed RA, Wu J, Ravindranathan A, Shai A, Oberheim Bush NA, Taylor JW, de Groot J, Villanueva-Meyer JE, Pekmezci M, Perry A, Bollen AW, Theodosopoulos PV, Aghi MK, Chang EF, Hervey-Jumper SL, Raleigh DR, Molinaro AM, Costello JF, Diaz AA, Clarke JL, Butowski NA, Phillips JJ, Chang SM, Berger MS, Solomon DA. Lucas CG, et al. Among authors: costello jf. Neuro Oncol. 2024 Nov 19:noae214. doi: 10.1093/neuonc/noae214. Online ahead of print. Neuro Oncol. 2024. PMID: 39560080

10

Activating the dark genome to illuminate cancer vaccine targets.

Kwok DW, Okada H, Costello JF. Kwok DW, et al. Among authors: costello jf. Nat Genet. 2024 Sep;56(9):1770-1771. doi: 10.1038/s41588-024-01850-3. Nat Genet. 2024. PMID: 39223317

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