Moir RD - Search Results

1

Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors.

Huang X, Atwood CS, Moir RD, Hartshorn MA, Vonsattel JP, Tanzi RE, Bush AI. Huang X, et al. Among authors: moir rd. J Biol Chem. 1997 Oct 17;272(42):26464-70. doi: 10.1074/jbc.272.42.26464. J Biol Chem. 1997. PMID: 9334223 Free article.

2

Peroxidase activity of cyclooxygenase-2 (COX-2) cross-links beta-amyloid (Abeta) and generates Abeta-COX-2 hetero-oligomers that are increased in Alzheimer's disease.

Nagano S, Huang X, Moir RD, Payton SM, Tanzi RE, Bush AI. Nagano S, et al. Among authors: moir rd. J Biol Chem. 2004 Apr 9;279(15):14673-8. doi: 10.1074/jbc.M313003200. Epub 2004 Jan 14. J Biol Chem. 2004. PMID: 14724276 Free article.

3

Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides.

Huang X, Atwood CS, Moir RD, Hartshorn MA, Tanzi RE, Bush AI. Huang X, et al. Among authors: moir rd. J Biol Inorg Chem. 2004 Dec;9(8):954-60. doi: 10.1007/s00775-004-0602-8. Epub 2004 Nov 3. J Biol Inorg Chem. 2004. PMID: 15578276

4

Autoantibodies to redox-modified oligomeric Abeta are attenuated in the plasma of Alzheimer's disease patients.

Moir RD, Tseitlin KA, Soscia S, Hyman BT, Irizarry MC, Tanzi RE. Moir RD, et al. J Biol Chem. 2005 Apr 29;280(17):17458-63. doi: 10.1074/jbc.M414176200. Epub 2005 Feb 21. J Biol Chem. 2005. PMID: 15728175 Free article.

5

Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells.

Kim TW, Pettingell WH, Hallmark OG, Moir RD, Wasco W, Tanzi RE. Kim TW, et al. Among authors: moir rd. J Biol Chem. 1997 Apr 25;272(17):11006-10. doi: 10.1074/jbc.272.17.11006. J Biol Chem. 1997. PMID: 9110991 Free article.

6

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

Atwood CS, Moir RD, Huang X, Scarpa RC, Bacarra NM, Romano DM, Hartshorn MA, Tanzi RE, Bush AI. Atwood CS, et al. Among authors: moir rd. J Biol Chem. 1998 May 22;273(21):12817-26. doi: 10.1074/jbc.273.21.12817. J Biol Chem. 1998. PMID: 9582309 Free article.

7

Role of free radicals and metal ions in the pathogenesis of Alzheimer's disease.

Atwood CS, Huang X, Moir RD, Tanzi RE, Bush AI. Atwood CS, et al. Among authors: moir rd. Met Ions Biol Syst. 1999;36:309-64. Met Ions Biol Syst. 1999. PMID: 10093929 Review. No abstract available.

8

Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations.

Moir RD, Atwood CS, Romano DM, Laurans MH, Huang X, Bush AI, Smith JD, Tanzi RE. Moir RD, et al. Biochemistry. 1999 Apr 6;38(14):4595-603. doi: 10.1021/bi982437d. Biochemistry. 1999. PMID: 10194381

9

Mounting evidence for the involvement of zinc and copper in Alzheimer's disease.

Moir RD, Atwood CS, Huang X, Tanzi RE, Bush AI. Moir RD, et al. Eur J Clin Invest. 1999 Jul;29(7):569-70. doi: 10.1046/j.1365-2362.1999.00472.x. Eur J Clin Invest. 1999. PMID: 10411660 Review. No abstract available.

10

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

Huang X, Cuajungco MP, Atwood CS, Hartshorn MA, Tyndall JD, Hanson GR, Stokes KC, Leopold M, Multhaup G, Goldstein LE, Scarpa RC, Saunders AJ, Lim J, Moir RD, Glabe C, Bowden EF, Masters CL, Fairlie DP, Tanzi RE, Bush AI. Huang X, et al. Among authors: moir rd. J Biol Chem. 1999 Dec 24;274(52):37111-6. doi: 10.1074/jbc.274.52.37111. J Biol Chem. 1999. PMID: 10601271 Free article.

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