Huber R - Search Results

1

Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug.

Fuentes-Prior P, Noeske-Jungblut C, Donner P, Schleuning WD, Huber R, Bode W. Fuentes-Prior P, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11845-50. doi: 10.1073/pnas.94.22.11845. Proc Natl Acad Sci U S A. 1997. PMID: 9342325 Free PMC article.

2

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism.

Engel M, Hoffmann T, Wagner L, Wermann M, Heiser U, Kiefersauer R, Huber R, Bode W, Demuth HU, Brandstetter H. Engel M, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5063-8. doi: 10.1073/pnas.0230620100. Epub 2003 Apr 10. Proc Natl Acad Sci U S A. 2003. PMID: 12690074 Free PMC article.

3

Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor.

Richardson JL, Fuentes-Prior P, Sadler JE, Huber R, Bode W. Richardson JL, et al. Among authors: huber r. Biochemistry. 2002 Feb 26;41(8):2535-42. doi: 10.1021/bi011605q. Biochemistry. 2002. PMID: 11851400

4

The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.

Than ME, Henrich S, Huber R, Ries A, Mann K, Kühn K, Timpl R, Bourenkov GP, Bartunik HD, Bode W. Than ME, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6607-12. doi: 10.1073/pnas.062183499. Proc Natl Acad Sci U S A. 2002. PMID: 12011424 Free PMC article.

5

Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin.

Stubbs MT, Huber R, Bode W. Stubbs MT, et al. Among authors: huber r. FEBS Lett. 1995 Nov 13;375(1-2):103-7. doi: 10.1016/0014-5793(95)01190-p. FEBS Lett. 1995. PMID: 7498454 Free article.

6

X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.

Brandstetter H, Bauer M, Huber R, Lollar P, Bode W. Brandstetter H, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9796-800. doi: 10.1073/pnas.92.21.9796. Proc Natl Acad Sci U S A. 1995. PMID: 7568220 Free PMC article.

7

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.

Maskos K, Fernandez-Catalan C, Huber R, Bourenkov GP, Bartunik H, Ellestad GA, Reddy P, Wolfson MF, Rauch CT, Castner BJ, Davis R, Clarke HR, Petersen M, Fitzner JN, Cerretti DP, March CJ, Paxton RJ, Black RA, Bode W. Maskos K, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3408-12. doi: 10.1073/pnas.95.7.3408. Proc Natl Acad Sci U S A. 1998. PMID: 9520379 Free PMC article.

8

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex.

Fuentes-Prior P, Iwanaga Y, Huber R, Pagila R, Rumennik G, Seto M, Morser J, Light DR, Bode W. Fuentes-Prior P, et al. Among authors: huber r. Nature. 2000 Mar 30;404(6777):518-25. doi: 10.1038/35006683. Nature. 2000. PMID: 10761923

9

(4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase.

Sperl S, Jacob U, Arroyo de Prada N, Stürzebecher J, Wilhelm OG, Bode W, Magdolen V, Huber R, Moroder L. Sperl S, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5113-8. doi: 10.1073/pnas.97.10.5113. Proc Natl Acad Sci U S A. 2000. PMID: 10805774 Free PMC article.

10

Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor.

Richardson JL, Kröger B, Hoeffken W, Sadler JE, Pereira P, Huber R, Bode W, Fuentes-Prior P. Richardson JL, et al. Among authors: huber r. EMBO J. 2000 Nov 1;19(21):5650-60. doi: 10.1093/emboj/19.21.5650. EMBO J. 2000. PMID: 11060016 Free PMC article.

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