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A phase I study of the GM-CSF antagonist E21R.
Olver IN, Hercus T, Lopez A, Vadas M, Somogyi AA, Doyle I, Foster DJ, Keefe D, Taylor A, Brown M, To LB, Cole J, Rawling T, Cambareri B, Myers M, Olszewski N, Bastiras S, Senn C, Hey A, Verma M, Wigley P. Olver IN, et al. Among authors: bastiras s. Cancer Chemother Pharmacol. 2002 Sep;50(3):171-8. doi: 10.1007/s00280-002-0474-y. Epub 2002 Jul 3. Cancer Chemother Pharmacol. 2002. PMID: 12203098 Clinical Trial.
Evidence for involvement of the carboxy terminus of helix 1 of growth hormone in receptor binding: use of charge reversal mutagenesis to account for calcium dependence of binding and for design of higher affinity analogues.
Rowlinson SW, Barnard R, Bastiras S, Robins AJ, Senn C, Wells JR, Brinkworth R, Waters MJ. Rowlinson SW, et al. Among authors: bastiras s. Biochemistry. 1994 Oct 4;33(39):11724-33. doi: 10.1021/bi00205a008. Biochemistry. 1994. PMID: 7918389
Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.
Bathgate RA, Lin F, Hanson NF, Otvos L Jr, Guidolin A, Giannakis C, Bastiras S, Layfield SL, Ferraro T, Ma S, Zhao C, Gundlach AL, Samuel CS, Tregear GW, Wade JD. Bathgate RA, et al. Among authors: bastiras s. Biochemistry. 2006 Jan 24;45(3):1043-53. doi: 10.1021/bi052233e. Biochemistry. 2006. PMID: 16411781
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