Roberts CJ - Search Results

1

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints.

Cliby WA, Roberts CJ, Cimprich KA, Stringer CM, Lamb JR, Schreiber SL, Friend SH. Cliby WA, et al. Among authors: roberts cj. EMBO J. 1998 Jan 2;17(1):159-69. doi: 10.1093/emboj/17.1.159. EMBO J. 1998. PMID: 9427750 Free PMC article.

2

Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae.

Simon JA, Szankasi P, Nguyen DK, Ludlow C, Dunstan HM, Roberts CJ, Jensen EL, Hartwell LH, Friend SH. Simon JA, et al. Among authors: roberts cj. Cancer Res. 2000 Jan 15;60(2):328-33. Cancer Res. 2000. PMID: 10667584

3

Integrating genetic approaches into the discovery of anticancer drugs.

Hartwell LH, Szankasi P, Roberts CJ, Murray AW, Friend SH. Hartwell LH, et al. Among authors: roberts cj. Science. 1997 Nov 7;278(5340):1064-8. doi: 10.1126/science.278.5340.1064. Science. 1997. PMID: 9353181 Review.

4

Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles.

Roberts CJ, Nelson B, Marton MJ, Stoughton R, Meyer MR, Bennett HA, He YD, Dai H, Walker WL, Hughes TR, Tyers M, Boone C, Friend SH. Roberts CJ, et al. Science. 2000 Feb 4;287(5454):873-80. doi: 10.1126/science.287.5454.873. Science. 2000. PMID: 10657304

5

Genetic selection of peptide inhibitors of biological pathways.

Norman TC, Smith DL, Sorger PK, Drees BL, O'Rourke SM, Hughes TR, Roberts CJ, Friend SH, Fields S, Murray AW. Norman TC, et al. Among authors: roberts cj. Science. 1999 Jul 23;285(5427):591-5. doi: 10.1126/science.285.5427.591. Science. 1999. PMID: 10417390

6

A survey of cancer cell lines reveals highly structured and hierarchical relationships within and between DNA and mRNA that may be the result of selection.

Xie T, Zhang C, Zhang B, Molony C, Oudes A, Roberts C, Dai H, Schadt E, Lamb J. Xie T, et al. OMICS. 2010 Feb;14(1):91-7. doi: 10.1089/omi.2009.0114. OMICS. 2010. PMID: 20141331

7

Widespread aneuploidy revealed by DNA microarray expression profiling.

Hughes TR, Roberts CJ, Dai H, Jones AR, Meyer MR, Slade D, Burchard J, Dow S, Ward TR, Kidd MJ, Friend SH, Marton MJ. Hughes TR, et al. Among authors: roberts cj. Nat Genet. 2000 Jul;25(3):333-7. doi: 10.1038/77116. Nat Genet. 2000. PMID: 10888885

8

Drug target validation and identification of secondary drug target effects using DNA microarrays.

Marton MJ, DeRisi JL, Bennett HA, Iyer VR, Meyer MR, Roberts CJ, Stoughton R, Burchard J, Slade D, Dai H, Bassett DE Jr, Hartwell LH, Brown PO, Friend SH. Marton MJ, et al. Among authors: roberts cj. Nat Med. 1998 Nov;4(11):1293-301. doi: 10.1038/3282. Nat Med. 1998. PMID: 9809554

9

A gene-expression signature as a predictor of survival in breast cancer.

van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, Voskuil DW, Schreiber GJ, Peterse JL, Roberts C, Marton MJ, Parrish M, Atsma D, Witteveen A, Glas A, Delahaye L, van der Velde T, Bartelink H, Rodenhuis S, Rutgers ET, Friend SH, Bernards R. van de Vijver MJ, et al. N Engl J Med. 2002 Dec 19;347(25):1999-2009. doi: 10.1056/NEJMoa021967. N Engl J Med. 2002. PMID: 12490681 Free article.

10

Gene expression profiling predicts clinical outcome of breast cancer.

van 't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R, Friend SH. van 't Veer LJ, et al. Nature. 2002 Jan 31;415(6871):530-6. doi: 10.1038/415530a. Nature. 2002. PMID: 11823860

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