Katz AH - Search Results

1

New generation dopaminergic agents. 1. Discovery of a novel scaffold which embraces the D2 agonist pharmacophore. Structure-activity relationships of a series of 2-(aminomethyl)chromans.

Mewshaw RE, Kavanagh J, Stack G, Marquis KL, Shi X, Kagan MZ, Webb MB, Katz AH, Park A, Kang YH, Abou-Gharbia M, Scerni R, Wasik T, Cortes-Burgos L, Spangler T, Brennan JA, Piesla M, Mazandarani H, Cockett MI, Ochalski R, Coupet J, Andree TH. Mewshaw RE, et al. Among authors: katz ah. J Med Chem. 1997 Dec 19;40(26):4235-56. doi: 10.1021/jm9703653. J Med Chem. 1997. PMID: 9435894

2

Design, synthesis, SAR, and biological evaluation of highly potent benzimidazole-spaced phosphono-alpha-amino acid competitive NMDA antagonists of the AP-6 type.

Baudy RB, Fletcher H 3rd, Yardley JP, Zaleska MM, Bramlett DR, Tasse RP, Kowal DM, Katz AH, Moyer JA, Abou-Gharbia M. Baudy RB, et al. Among authors: katz ah. J Med Chem. 2001 May 10;44(10):1516-29. doi: 10.1021/jm000385w. J Med Chem. 2001. PMID: 11334562

3

Structure-activity relationships among analogues of pemedolac, cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]indo le-1-a cetic acid, a potent analgesic agent.

Mobilio D, Humber LG, Katz AH, Demerson CA, Hughes P, Brigance R, Conway K, Shah U, Williams G, Labbadia F, et al. Mobilio D, et al. Among authors: katz ah. J Med Chem. 1988 Nov;31(11):2211-7. doi: 10.1021/jm00119a024. J Med Chem. 1988. PMID: 3263504

4

PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes.

Wrobel J, Sredy J, Moxham C, Dietrich A, Li Z, Sawicki DR, Seestaller L, Wu L, Katz A, Sullivan D, Tio C, Zhang ZY. Wrobel J, et al. J Med Chem. 1999 Aug 26;42(17):3199-202. doi: 10.1021/jm990260v. J Med Chem. 1999. PMID: 10464006 No abstract available.

5

Synthesis and analgesic activity of pemedolac (cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]ind ole-1- acetic acid).

Katz AH, Demerson CA, Shaw CC, Asselin AA, Humber LG, Conway KM, Gavin G, Guinosso C, Jensen NP, Mobilio D, et al. Katz AH, et al. J Med Chem. 1988 Jun;31(6):1244-50. doi: 10.1021/jm00401a029. J Med Chem. 1988. PMID: 3373493

6

New modified heterocyclic phenylalanine derivatives. Incorporation into potent inhibitors of human renin.

Ocain TD, Deininger DD, Russo R, Senko NA, Katz A, Kitzen JM, Mitchell R, Oshiro G, Russo A, Stupienski R, et al. Ocain TD, et al. J Med Chem. 1992 Mar 6;35(5):823-32. doi: 10.1021/jm00083a005. J Med Chem. 1992. PMID: 1548674

7

Novel benzofuran and benzothiophene biphenyls as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties.

Malamas MS, Sredy J, Moxham C, Katz A, Xu W, McDevitt R, Adebayo FO, Sawicki DR, Seestaller L, Sullivan D, Taylor JR. Malamas MS, et al. J Med Chem. 2000 Apr 6;43(7):1293-310. doi: 10.1021/jm990560c. J Med Chem. 2000. PMID: 10753467

8

Pyrazolidine-3,5-diones and 5-hydroxy-1H-pyrazol-3(2H)-ones, inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase.

Gilbert AM, Failli A, Shumsky J, Yang Y, Severin A, Singh G, Hu W, Keeney D, Petersen PJ, Katz AH. Gilbert AM, et al. Among authors: katz ah. J Med Chem. 2006 Oct 5;49(20):6027-36. doi: 10.1021/jm060499t. J Med Chem. 2006. PMID: 17004716

9

Identification and characterization of small molecule modulators of KChIP/Kv4 function.

Bowlby MR, Chanda P, Edris W, Hinson J, Jow F, Katz AH, Kennedy J, Krishnamurthy G, Pitts K, Ryan K, Zhang H, Greenblatt L. Bowlby MR, et al. Among authors: katz ah. Bioorg Med Chem. 2005 Nov 15;13(22):6112-9. doi: 10.1016/j.bmc.2005.06.042. Epub 2005 Aug 2. Bioorg Med Chem. 2005. PMID: 16081294

10

4-Alkyl and 4,4'-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis.

Kutterer KM, Davis JM, Singh G, Yang Y, Hu W, Severin A, Rasmussen BA, Krishnamurthy G, Failli A, Katz AH. Kutterer KM, et al. Among authors: katz ah. Bioorg Med Chem Lett. 2005 May 16;15(10):2527-31. doi: 10.1016/j.bmcl.2005.03.058. Bioorg Med Chem Lett. 2005. PMID: 15863310

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