Homology modeling with internal coordinate mechanics: deformation zone mapping and improvements of models via conformational search.
Abagyan R, Batalov S, Cardozo T, Totrov M, Webber J, Zhou Y.
Abagyan R, et al.
Proteins. 1997;Suppl 1:29-37. doi: 10.1002/(sici)1097-0134(1997)1+<29::aid-prot5>3.3.co;2-4.
Proteins. 1997.
PMID: 9485492
For all five low identity targets: (i) our starting models were improved by the Internal Coordinate Mechanics (ICM) energy optimization, (ii) the refined models were consistently better than those built with the automatic SWISS-MODEL program, and (iii) the refined models differed …
For all five low identity targets: (i) our starting models were improved by the Internal Coordinate Mechanics (ICM) energy optimization, (ii …