Rewcastle GW - Search Results

1

Tyrosine kinase inhibitors. 14. Structure-activity relationships for methylamino-substituted derivatives of 4-[(3-bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyrimidine (PD 158780), a potent and specific inhibitor of the tyrosine kinase activity of receptors for the EGF family of growth factors.

Rewcastle GW, Murray DK, Elliott WL, Fry DW, Howard CT, Nelson JM, Roberts BJ, Vincent PW, Showalter HD, Winters RT, Denny WA. Rewcastle GW, et al. J Med Chem. 1998 Feb 26;41(5):742-51. doi: 10.1021/jm970641d. J Med Chem. 1998. PMID: 9513602

2

Structure-activity relationships for substituted 9-oxo-9,10-dihydroacridine-4-acetic acids: analogues of the colon tumour active agent xanthenone-4-acetic acid.

Gamage SA, Rewcastle GW, Atwell GJ, Baguley BC, Denny WA. Gamage SA, et al. Among authors: rewcastle gw. Anticancer Drug Des. 1992 Oct;7(5):403-14. Anticancer Drug Des. 1992. PMID: 1388631

3

Induction of natural killer activity by xanthenone analogues of flavone acetic acid: relation with antitumour activity.

Ching LM, Joseph WR, Zhuang L, Atwell GJ, Rewcastle GW, Denny WA, Baguley BC. Ching LM, et al. Among authors: rewcastle gw. Eur J Cancer. 1991;27(1):79-83. doi: 10.1016/0277-5379(91)90067-n. Eur J Cancer. 1991. PMID: 1826446

4

Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid.

Rewcastle GW, Atwell GJ, Baguley BC, Boyd M, Thomsen LL, Zhuang L, Denny WA. Rewcastle GW, et al. J Med Chem. 1991 Sep;34(9):2864-70. doi: 10.1021/jm00113a027. J Med Chem. 1991. PMID: 1895304

5

Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids.

Rewcastle GW, Atwell GJ, Li ZA, Baguley BC, Denny WA. Rewcastle GW, et al. J Med Chem. 1991 Jan;34(1):217-22. doi: 10.1021/jm00105a034. J Med Chem. 1991. PMID: 1992120

6

Potential antitumor agents. 62. Structure-activity relationships for tricyclic compounds related to the colon tumor active drug 9-oxo-9H-xanthene-4-acetic acid.

Rewcastle GW, Atwell GJ, Palmer BD, Boyd PD, Baguley BC, Denny WA. Rewcastle GW, et al. J Med Chem. 1991 Feb;34(2):491-6. doi: 10.1021/jm00106a003. J Med Chem. 1991. PMID: 1995870

7

Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of "minimal" DNA-intercalating agents which may not act via topoisomerase II.

Denny WA, Rewcastle GW, Baguley BC. Denny WA, et al. Among authors: rewcastle gw. J Med Chem. 1990 Feb;33(2):814-9. doi: 10.1021/jm00164a054. J Med Chem. 1990. PMID: 2153829

8

Structure-activity relationships for the mutagenic activity of tricyclic intercalating agents in Salmonella typhimurium.

Denny WA, Turner PM, Atwell GJ, Rewcastle GW, Ferguson LR. Denny WA, et al. Among authors: rewcastle gw. Mutat Res. 1990 Oct;232(2):233-41. doi: 10.1016/0027-5107(90)90129-r. Mutat Res. 1990. PMID: 2215533

9

Light-induced breakdown of flavone acetic acid and xanthenone analogues in solution.

Rewcastle GW, Kestell P, Baguley BC, Denny WA. Rewcastle GW, et al. J Natl Cancer Inst. 1990 Mar 21;82(6):528-9. doi: 10.1093/jnci/82.6.528. J Natl Cancer Inst. 1990. PMID: 2313725 No abstract available.

10

Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids.

Atwell GJ, Rewcastle GW, Baguley BC, Denny WA. Atwell GJ, et al. Among authors: rewcastle gw. J Med Chem. 1990 May;33(5):1375-9. doi: 10.1021/jm00167a015. J Med Chem. 1990. PMID: 2329557

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