Imbach JL - Search Results

1

Comparison of the disposition of ester prodrugs of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine [PMEA] in Caco-2 monolayers.

Annaert P, Gosselin G, Pompon A, Benzaria S, Valette G, Imbach JL, Naesens L, Hatse S, de Clercq E, Van den Mooter G, Kinget R, Augustijns P. Annaert P, et al. Among authors: imbach jl. Pharm Res. 1998 Feb;15(2):239-45. doi: 10.1023/a:1011914618109. Pharm Res. 1998. PMID: 9523310

2

New bis(SATE) prodrug of AZT 5'-monophosphate: in vitro anti-HIV activity, stability, and potential oral absorption.

Shafiee M, Deferme S, Villard AL, Egron D, Gosselin G, Imbach JL, Lioux T, Pompon A, Varray S, Aubertin AM, Van Den Mooter G, Kinget R, Périgaud C, Augustijns P. Shafiee M, et al. Among authors: imbach jl. J Pharm Sci. 2001 Apr;90(4):448-63. doi: 10.1002/1520-6017(200104)90:4<448::aid-jps1003>3.0.co;2-h. J Pharm Sci. 2001. PMID: 11170035

3

Synthesis, in vitro antiviral evaluation, and stability studies of bis(S-acyl-2-thioethyl) ester derivatives of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) as potential PMEA prodrugs with improved oral bioavailability.

Benzaria S, Pélicano H, Johnson R, Maury G, Imbach JL, Aubertin AM, Obert G, Gosselin G. Benzaria S, et al. Among authors: imbach jl. J Med Chem. 1996 Dec 6;39(25):4958-65. doi: 10.1021/jm960289o. J Med Chem. 1996. PMID: 8960556

4

Intracellular delivery of nucleoside monophosphates through a reductase-mediated activation process.

Puech F, Gosselin G, Lefebvre I, Pompon A, Aubertin AM, Kirn A, Imbach JL. Puech F, et al. Among authors: imbach jl. Antiviral Res. 1993 Oct;22(2-3):155-74. doi: 10.1016/0166-3542(93)90093-x. Antiviral Res. 1993. PMID: 8279810

5

New insights regarding the potential of the pronucleotide approach in antiviral chemotherapy.

Gosselin G, Girardet JL, Périgaud C, Benzaria S, Lefebvre I, Schlienger N, Pompon A, Imbach JL. Gosselin G, et al. Among authors: imbach jl. Acta Biochim Pol. 1996;43(1):196-208. Acta Biochim Pol. 1996. PMID: 8790724 Review.

6

Synthesis of new PMEA diphosphate mimics.

Laux WH, Périgaud C, Imbach JL, Gosselin G. Laux WH, et al. Among authors: imbach jl. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):1003-4. doi: 10.1080/15257779908041629. Nucleosides Nucleotides. 1999. PMID: 10432730

7

Anti-human immunodeficiency virus type 1 activities of dideoxynucleoside phosphotriester derivatives in primary monocytes/macrophages.

Thumann-Schweitzer C, Gosselin G, Périgaud C, Benzaria S, Girardet JL, Lefebvre I, Imbach JL, Kirn A, Aubertin AM. Thumann-Schweitzer C, et al. Among authors: imbach jl. Res Virol. 1996 Mar-Jun;147(2-3):155-63. doi: 10.1016/0923-2516(96)80230-5. Res Virol. 1996. PMID: 8901435

8

The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir: part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir.

Périgaud C, Gosselin G, Girardet JL, Korba BE, Imbach JL. Périgaud C, et al. Among authors: imbach jl. Antiviral Res. 1999 Jan;40(3):167-78. doi: 10.1016/s0166-3542(98)00059-x. Antiviral Res. 1999. PMID: 10027651

9

Synthesis and antiviral evaluation of SATE-foscarnet prodrugs and new foscarnet-AZT conjugates.

Meier C, Aubertin AM, de Monte M, Faraj A, Sommadossi JP, Périgaud C, Imbach JL, Gosselin G. Meier C, et al. Among authors: imbach jl. Antivir Chem Chemother. 1998 Jan;9(1):41-52. doi: 10.1177/095632029800900105. Antivir Chem Chemother. 1998. PMID: 9875376

10

Synthesis and study of a new series of phosphoramidate derivatives as mononucleotide prodrugs.

Egron D, Périgaud C, Gosselin G, Aubertin AM, Imbach JL. Egron D, et al. Among authors: imbach jl. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):751-4. doi: 10.1081/NCN-100002422. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563108

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