Afar DE - Search Results

1

Bcl-2-independent Bcr-Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL.

Amarante-Mendes GP, McGahon AJ, Nishioka WK, Afar DE, Witte ON, Green DR. Amarante-Mendes GP, et al. Among authors: afar de. Oncogene. 1998 Mar;16(11):1383-90. doi: 10.1038/sj.onc.1201664. Oncogene. 1998. PMID: 9525737

2

Regulation of the oncogenic activity of BCR-ABL by a tightly bound substrate protein RIN1.

Afar DE, Han L, McLaughlin J, Wong S, Dhaka A, Parmar K, Rosenberg N, Witte ON, Colicelli J. Afar DE, et al. Immunity. 1997 Jun;6(6):773-82. doi: 10.1016/s1074-7613(00)80452-5. Immunity. 1997. PMID: 9208849 Free article.

3

Characterization of breakpoint cluster region kinase and SH2-binding activities.

Afar DE, Witte ON. Afar DE, et al. Methods Enzymol. 1995;256:125-9. doi: 10.1016/0076-6879(95)56017-3. Methods Enzymol. 1995. PMID: 7476425

4

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene.

Goga A, McLaughlin J, Afar DE, Saffran DC, Witte ON. Goga A, et al. Among authors: afar de. Cell. 1995 Sep 22;82(6):981-8. doi: 10.1016/0092-8674(95)90277-5. Cell. 1995. PMID: 7553858 Free article.

5

Signaling by ABL oncogenes through cyclin D1.

Afar DE, McLaughlin J, Sherr CJ, Witte ON, Roussel MF. Afar DE, et al. Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9540-4. doi: 10.1073/pnas.92.21.9540. Proc Natl Acad Sci U S A. 1995. PMID: 7568169 Free PMC article.

6

Differential complementation of Bcr-Abl point mutants with c-Myc.

Afar DE, Goga A, McLaughlin J, Witte ON, Sawyers CL. Afar DE, et al. Science. 1994 Apr 15;264(5157):424-6. doi: 10.1126/science.8153630. Science. 1994. PMID: 8153630

7

Dissection of signaling pathways and cloning of new signal transducers in tyrosine kinase-induced pathways by genetic selection.

Mahlmann S, McLaughlin J, Afar DE, Mohr R, Kay RJ, Witte ON. Mahlmann S, et al. Among authors: afar de. Leukemia. 1998 Dec;12(12):1858-65. doi: 10.1038/sj.leu.2401231. Leukemia. 1998. PMID: 9844916 Review.

8

Genetic approaches to defining signaling by the CML-associated tyrosine kinase BCR-ABL.

Afar DE, Goga A, Cohen L, Sawyers CL, McLaughlin J, Mohr RN, Witte ON. Afar DE, et al. Cold Spring Harb Symp Quant Biol. 1994;59:589-94. doi: 10.1101/sqb.1994.059.01.067. Cold Spring Harb Symp Quant Biol. 1994. PMID: 7587117 Review. No abstract available.

9

The dimerization property of glutathione S-transferase partially reactivates Bcr-Abl lacking the oligomerization domain.

Maru Y, Afar DE, Witte ON, Shibuya M. Maru Y, et al. Among authors: afar de. J Biol Chem. 1996 Jun 28;271(26):15353-7. doi: 10.1074/jbc.271.26.15353. J Biol Chem. 1996. PMID: 8663064 Free article.

10

Recognition of multiple substrate motifs by the c-ABL protein tyrosine kinase.

Wu JJ, Afar DE, Phan H, Witte ON, Lam KS. Wu JJ, et al. Among authors: afar de. Comb Chem High Throughput Screen. 2002 Feb;5(1):83-91. doi: 10.2174/1386207023330516. Comb Chem High Throughput Screen. 2002. PMID: 11860343

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