Lehrach H - Search Results

1

Ataxin-3 is transported into the nucleus and associates with the nuclear matrix.

Tait D, Riccio M, Sittler A, Scherzinger E, Santi S, Ognibene A, Maraldi NM, Lehrach H, Wanker EE. Tait D, et al. Among authors: lehrach h. Hum Mol Genet. 1998 Jun;7(6):991-7. doi: 10.1093/hmg/7.6.991. Hum Mol Genet. 1998. PMID: 9580663

2

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.

Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE. Sittler A, et al. Among authors: lehrach h. Mol Cell. 1998 Oct;2(4):427-36. doi: 10.1016/s1097-2765(00)80142-2. Mol Cell. 1998. PMID: 9809064 Free article.

3

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.

Scherzinger E, Sittler A, Schweiger K, Heiser V, Lurz R, Hasenbank R, Bates GP, Lehrach H, Wanker EE. Scherzinger E, et al. Among authors: lehrach h. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4604-9. doi: 10.1073/pnas.96.8.4604. Proc Natl Acad Sci U S A. 1999. PMID: 10200309 Free PMC article.

4

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease.

Sittler A, Lurz R, Lueder G, Priller J, Lehrach H, Hayer-Hartl MK, Hartl FU, Wanker EE. Sittler A, et al. Among authors: lehrach h. Hum Mol Genet. 2001 Jun 1;10(12):1307-15. doi: 10.1093/hmg/10.12.1307. Hum Mol Genet. 2001. PMID: 11406612

5

The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis.

Waelter S, Scherzinger E, Hasenbank R, Nordhoff E, Lurz R, Goehler H, Gauss C, Sathasivam K, Bates GP, Lehrach H, Wanker EE. Waelter S, et al. Among authors: lehrach h. Hum Mol Genet. 2001 Aug 15;10(17):1807-17. doi: 10.1093/hmg/10.17.1807. Hum Mol Genet. 2001. PMID: 11532990

6

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system.

Wanker EE, Rovira C, Scherzinger E, Hasenbank R, Wälter S, Tait D, Colicelli J, Lehrach H. Wanker EE, et al. Among authors: lehrach h. Hum Mol Genet. 1997 Mar;6(3):487-95. doi: 10.1093/hmg/6.3.487. Hum Mol Genet. 1997. PMID: 9147654

7

Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.

Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE. Busch A, et al. Among authors: lehrach h. J Biol Chem. 2003 Oct 17;278(42):41452-61. doi: 10.1074/jbc.M303354200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888569 Free article.

8

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.

Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, Droege A, Lindenberg KS, Knoblich M, Haenig C, Herbst M, Suopanki J, Scherzinger E, Abraham C, Bauer B, Hasenbank R, Fritzsche A, Ludewig AH, Büssow K, Coleman SH, Gutekunst CA, Landwehrmeyer BG, Lehrach H, Wanker EE. Goehler H, et al. Among authors: lehrach h. Mol Cell. 2004 Sep 24;15(6):853-65. doi: 10.1016/j.molcel.2004.09.016. Mol Cell. 2004. PMID: 15383276 Free article.

9

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.

Scherzinger E, Lurz R, Turmaine M, Mangiarini L, Hollenbach B, Hasenbank R, Bates GP, Davies SW, Lehrach H, Wanker EE. Scherzinger E, et al. Among authors: lehrach h. Cell. 1997 Aug 8;90(3):549-58. doi: 10.1016/s0092-8674(00)80514-0. Cell. 1997. PMID: 9267034 Free article.

10

Huntingtin aggregation monitored by dynamic light scattering.

Georgalis Y, Starikov EB, Hollenbach B, Lurz R, Scherzinger E, Saenger W, Lehrach H, Wanker EE. Georgalis Y, et al. Among authors: lehrach h. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6118-21. doi: 10.1073/pnas.95.11.6118. Proc Natl Acad Sci U S A. 1998. PMID: 9600927 Free PMC article.

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